Evaluation of an automated module synthesis and a sterile cold kit–based preparation of 68Ga-PSMA-11 in patients with prostate cancer

L Calderoni, A Farolfi, D Pianori, E Maietti… - Journal of Nuclear …, 2020 - Soc Nuclear Med
68Ga-labeled urea-based inhibitors of the prostate-specific membrane antigen (PSMA),
such as 68Ga-PSMA-11, are promising small molecules for targeting prostate cancer (PCa) …

[HTML][HTML] Standardization of the [68Ga]Ga-PSMA-11 Radiolabeling Protocol in an Automatic Synthesis Module: Assessments for PET Imaging of Prostate Cancer

LL Fuscaldi, DV Sobral, ACR Durante, FF Mendonça… - Pharmaceuticals, 2021 - mdpi.com
Prostate-specific membrane antigen (PSMA) is a glycoprotein present in the prostate, that is
overexpressed in prostate cancer (PCa). Recently, PSMA-directed radiopharmaceuticals …

Optimal time-point for 68Ga-PSMA-11 PET/CT imaging in assessment of prostate cancer: feasibility of sterile cold-kit tracer preparation?

M Beheshti, Z Paymani, J Brilhante, H Geinitz… - European Journal of …, 2018 - Springer
Purpose In this prospective study, we evaluated the optimal time-point for 68 Ga-PSMA-11
PET/CT acquisition in the assessment of prostate cancer. We also examined, for the first time …

Cold Kit PSMA PET Imaging: Phase I study of 68Ga-THP-PSMA PET/CT in patients with prostate cancer

MS Hofman, P Eu, P Jackson, E Hong… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Objectives: Ga-68 labelled urea-based inhibitors of the prostate-specific membrane antigen
(PSMA), such as 68 Ga-HBED-PSMA-11, are promising small molecules for targeting …

Prospective intra-individual blinded comparison of [18F]PSMA-1007 and [68 Ga]Ga-PSMA-11 PET/CT imaging in patients with confirmed prostate cancer

DA Pattison, M Debowski, B Gulhane… - European Journal of …, 2022 - Springer
Abstract Introduction [18F] PSMA-1007 has potential advantages over [68 Ga] Ga-PSMA-11,
although limited prospective data evaluating diagnostic performance exist. The aims of this …

Convenient Preparation of [68Ga]DKFZ-PSMA-11 Using a Robust Single-Vial Kit and Demonstration of Its Clinical Efficacy

D Satpati, A Shinto, KK Kamaleshwaran… - Molecular imaging and …, 2016 - Springer
Abstract Purpose [68 Ga] DKFZ-PSMA-11 has proved to be an important diagnostic
radiotracer for targeting prostate-specific membrane antigen (PSMA) overexpression in both …

[HTML][HTML] Diagnostic performance of 18F-PSMA-1007 PET/CT in patients with biochemical recurrent prostate cancer

K Rahbar, A Afshar-Oromieh, R Seifert… - European journal of …, 2018 - Springer
Purpose The introduction of ligands targeting prostate-specific membrane antigen (PSMA),
especially 68 Ga-PSMA-11, has changed the management of patients with prostate cancer …

[HTML][HTML] In vitro and in vivo comparative study of a novel 68Ga-labeled PSMA-targeted inhibitor and 68Ga-PSMA-11

H Chen, P Cai, Y Feng, Z Sun, Y Wang, Y Chen… - Scientific Reports, 2021 - nature.com
Abstract 68Ga-radiolabeled small molecules that specifically target prostate-specific
membrane antigen (PSMA) have been extensively investigated, and some of these tracers …

Biodistribution and radiation dosimetry of 68Ga-PSMA HBED CC—a PSMA specific probe for PET imaging of prostate cancer

CH Pfob, S Ziegler, FP Graner, M Köhner… - European journal of …, 2016 - Springer
Purpose Positron emission tomography (PET) agents targeting the prostate-specific
membrane antigen (PSMA) are currently under broad clinical and scientific investigation. 68 …

[HTML][HTML] Analysis of Pros and Cons in Using [68Ga]Ga-PSMA-11 and [18F]PSMA-1007: Production, Costs, and PET/CT Applications in Patients with Prostate Cancer

C Maisto, M Aurilio, A Morisco, R de Marino… - Molecules, 2022 - mdpi.com
The aim of this work is to compare [68Ga] Ga-PSMA-11 and [18F] PSMA-1007 PET/CT as
imaging agents in patients with prostate cancer (PCa). Comparisons were made by …