111In-cetuximab-F (ab′) 2 SPECT and 18F-FDG PET for prediction and response monitoring of combined-modality treatment of human head and neck carcinomas in …

LK van Dijk, OC Boerman, GM Franssen… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Treatment of head and neck squamous cell carcinomas with radiotherapy and the epidermal
growth factor receptor (EGFR) inhibitor cetuximab shows an improved response in a …

Early response monitoring with 18F-FDG PET and cetuximab-F (ab′) 2-SPECT after radiotherapy of human head and neck squamous cell carcinomas in a mouse …

LK van Dijk, OC Boerman, GM Franssen… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Only a subset of patients with head and neck squamous cell carcinomas (HNSCCs) benefit
from radiotherapy and concurrent epidermal growth factor receptor (EGFR) inhibitor therapy …

Imaging of epidermal growth factor receptor expression in head and neck cancer with SPECT/CT and 111In-labeled cetuximab-F (ab′) 2

LK van Dijk, BAW Hoeben… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Combined treatment of advanced head and neck squamous cell carcinomas (HNSCC) with
radiotherapy and the epidermal growth factor receptor (EGFR) inhibitor cetuximab improves …

111In-cetuximab-F (ab') 2 SPECT imaging for quantification of accessible epidermal growth factor receptors (EGFR) in HNSCC xenografts

LK van Dijk, BAW Hoeben, H Stegeman… - Radiotherapy and …, 2013 - Elsevier
Background and purpose Immunohistochemical epidermal growth factor receptor (EGFR)
expression does not correlate with treatment response in head and neck squamous cell …

PET of EGFR with 64Cu‐cetuximab‐F(ab′)2 in mice with head and neck squamous cell carcinoma xenografts

LK van Dijk, CB Yim, GM Franssen… - Contrast Media & …, 2016 - Wiley Online Library
Overexpression of the epidermal growth factor receptor (EGFR) is linked to an adverse
outcome in various solid tumors. Cetuximab is an EGFR inhibitor, which in combination with …

Affibody-based PET imaging to guide EGFR-targeted cancer therapy in head and neck squamous cell cancer models

TA Burley, C Da Pieve, CD Martins… - Journal of Nuclear …, 2019 - Soc Nuclear Med
In head and neck squamous cell cancer, the human epidermal growth factor receptor 1
(EGFR) is the dominant signaling molecule among all members of the family. So far …

Evaluation of 18F‐FDG PET/CT as an early imaging biomarker for response monitoring after radiochemotherapy using cetuximab in head and heck squamous cell …

F de Galiza Barbosa, O Riesterer… - Head & …, 2020 - Wiley Online Library
Background To determine whether 18F‐PET/CT is able to identify treatment response as
early as 1 week after the end of chemoradiotherapy, whether 18F‐PET/CT can identify …

[HTML][HTML] Dose predictions for [177Lu]Lu-DOTA-panitumumab F(ab′)2 in NRG mice with HNSCC patient-derived tumour xenografts based on [64Cu]Cu-DOTA-panitumumab F …

A Ku, M Kondo, Z Cai, J Meens, MR Li, L Ailles… - EJNMMI …, 2021 - Springer
Background Epidermal growth factor receptors (EGFR) are overexpressed on many head
and neck squamous cell carcinoma (HNSCC). Radioimmunotherapy (RIT) with F (ab') 2 of …

PET imaging in head and neck cancer patients to monitor treatment response: a future role for EGFR-targeted imaging

LK van Dijk, OC Boerman, JHAM Kaanders… - Clinical Cancer …, 2015 - AACR
Approximately 50,000 new cases of head and neck squamous cell carcinoma (HNSCC) are
diagnosed worldwide each year and subsequently treated with surgery, chemotherapy …

[HTML][HTML] Immuno-PET imaging based radioimmunotherapy in head and neck squamous cell carcinoma model

IH Song, Y Noh, J Kwon, JH Jung, BC Lee, KI Kim… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The epidermal growth factor receptor (EGFR) is one of the most comprehensively studied
molecular targets in head and neck squamous cell carcinoma (HNSCC). However, inherent …