[PDF][PDF] Quantitative analyses of carbonyl-carbon-11-WAY-100635 binding to central 5-hydroxytryptamine-1A receptors in man

L Farde, H Ito, CG Swahn, VW Pike… - Journal of Nuclear …, 1998 - Soc Nuclear Med
Quantitative Analyses of Carbonyl-Carbon-11 - WAY-10063 5 Binding to Central 5-Hydroxytryptamine-lA
Receptors in Man Page 1 Quantitative Analyses of Carbonyl-Carbon-11 WAY-10063 5 …

Imaging the 5-HT1A receptors with PET: WAY-100635 and analogues

S Houle, JN DaSilva, AA Wilson - Nuclear medicine and biology, 2000 - Elsevier
This paper summarizes our work on WAY-100635 and analogues, labeled either with
carbon-11 or fluorine-18, as potential radioligands for the 5-hydroxytryptamine1A (5-HT1A) …

[carbonyl-11C]Desmethyl-WAY-100635 (DWAY) is a potent and selective radioligand for central 5-HT1A receptors in vitro and in vivo

VW Pike, C Halldin, JA McCarron, C Lundkvist… - European journal of …, 1998 - Springer
[carbonyl-11 C] Desmethyl-WAY-100635 (DWAY) is possibly a low-level metabolite
appearing in plasma after intravenous administration of [carbonyl-11 C] WAY-100635 to …

[PDF][PDF] Localization of 5-HT1A receptors in the living human brain using [carbonyl-11C] WAY-100635: PET with anatomic standardization technique

H Ito, C Halldin, L Farde - Journal of Nuclear Medicine, 1999 - Soc Nuclear Med
Serotonergic 5-hydroxytryptamine-1A (5-HT, A) receptors are of interest in the
pathophysiology of several neuropsychiatrie disor ders such as anxiety, depression and …

[PDF][PDF] PET imaging of central 5-HT2A receptors with carbon-11-MDL 100,907

H Ito, S Nyberg, C Halldin, C Lundkvist… - Journal of Nuclear …, 1998 - Soc Nuclear Med
à „erotonergic 5-HT2A receptors are of central interest in the complex pathophysiology of
schizophrenia (1-4). The 5-HT2A receptor has also been proposed as a putative target for …

Exquisite delineation of 5-HT1A receptors in human brain with PET and [carbonyl-11C] WAY-100635

VW Pike, JA McCarron, AA Lammertsma… - European journal of …, 1996 - Elsevier
The 5-HT1A receptor antagonist, WAY-100635 [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)
ethyl)-N-(2-pyridyl) cyclohexanecarboxamide], was labelled in its carbonyl group with …

Distribution of the 5‐hydroxytryptamine2C receptor protein in adult rat brain and spinal cord determined using a receptor‐directed antibody: Effect of 5,7 …

A Sharma, T Punhani, KCF Fone - Synapse, 1997 - Wiley Online Library
A synthetic peptide, corresponding to the N‐terminal decapeptide (+ Y11C12) of the rat 5‐
hydroxytryptamine2C (5‐HT2C) receptor protein was used to produce a sheep polyclonal …

Characterisation of the appearance of radioactive metabolites in monkey and human plasma from the 5-HT1A receptor radioligand,[carbonyl-11C] WAY-100635 …

S Osman, C Lundkvist, VW Pike, C Halldin… - Nuclear medicine and …, 1998 - Elsevier
N-(2-(4-(2-Methoxy-phenyl)-1-piperazin-1-yl) ethyl)-N-(2-pyridyl) cyclohexanecarboxamide
(WAY-100635), labelled in its amido carbonyl group with 11C (t1/2= 20.4 min), is a …

Identification of the ligand-binding subunit of the human 5-hydroxytryptamine1A receptor with N-(p-azido-m-[125I] iodophenethyl) spiperone, a high affinity …

JR Raymond, A Fargin, MJ Lohse, JW Regan… - Molecular …, 1989 - ASPET
The ligand-binding subunit of the human 5-hydroxytryptamine1A (5-HT1A) receptor
transiently expressed in COS-7 cells and of the native human 5-HT1A receptor derived from …

[PDF][PDF] PET studies on dopamine D1 receptors in the human brain with carbon-11-SCH 39166 and carbon-11-NNC 756

AO Laihinen, JO Rinne, HM Ruottinen… - Journal of Nuclear …, 1994 - Soc Nuclear Med
PET Studies on Dopamine Dl Receptors in the Human Brain with Carbon-11-SCH 39166
and Carbon-11-NNC 756 Page 1 affinity both for Dl receptors and also for 5-HT receptors (2) …