Our aim was to ascertain the relationship between the degree of 99mTc-MIBI uptake and the
level of p-glycoprotein (Pgp) expression determined by flow cytometry and reverse …

The ability of cancer cells to become simultaneously resistant to different drugs is a
significant impediment to successful chemotherapy. 99m Tc-MIBI has been reported to be a …

Expression of P-Glycoprotein in Lung Cancer Page 1 Association of Tumor Washout Rates
and Accumulation of Technetium-99m-MIBI with Expression of P-Glycoprotein in Lung Cancer …

P-glycoprotein (Pgp) overexpression has been shown to be correlated with resistance to
chemotherapy in patients with malignant bone and soft-tissue tumors. The aim of our study …

(B)++ strong; and (C) F+(arrows) focalp-glycoproteinstaining. Corresponding@ †œTc-MlBl
imagingonthispatientisshowninFigure3k Patient2:(D)++ strong;(E)+ weak; and (F) …

MATERIALS AND METhODS Patients Our study comprised 30 patients with various
malignant bone and soft-tissue tumors proven pathologically by specimens ob tamed from …

Background 99m Tc-methoxyisobutylisonitrile (99m Tc-MIBI) has been used as a tumour
positive scintigraphic agent for diagnostic purposes. However, the pharmaceutical kinetics …

Abstract Technetium-99m hexakis-2-methoxyisobutyl-isonitrile (MIBI) and thallium-201
imaging was performed in a patient with metastatic renal cell carcinoma (RCC), which is a …

Purpose Tc-99m MIBI is a promising agent for the functional characterization of P-
glycoprotein expression and the prediction of therapeutic outcome in human tumors. The …

Tc-99m MIBI is used as a tumor imaging agent and has been proposed to measure p-
glycoprotein function, which plays an important role in tumor multidrug resistance to …