Interim 18F-FDG PET in Hodgkin lymphoma: would PET-adapted clinical trials lead to a paradigm shift?

L Kostakoglu, A Gallamini - Journal of Nuclear Medicine, 2013 - Soc Nuclear Med
Hodgkin lymphoma (HL) is a curable disease with currently available chemotherapy
regimens. Major late morbidities can potentially be avoided in most limited-stage HL patients …

[HTML][HTML] Interim analysis of the randomized EORTC/LYSA/FIL intergroup H10 trial on early PET-scan driven treatment adaptation in stage I/II Hodgkin lymphoma

MPE André, O Reman, M Federico, T Girinski, P Brice… - Blood, 2012 - Elsevier
Abstract Abstract 549 Introduction Early stage classical Hodgkin lymphoma (cHL) is highly
curable with a combination of chemotherapy and radiotherapy (RT). Late toxicities due to RT …

The evolving role of response-adapted PET imaging in Hodgkin lymphoma

M Coyle, L Kostakoglu… - Therapeutic Advances in …, 2016 - journals.sagepub.com
18F-fluorodeoxyglucose positron emission tomography with (FDG-PET) has a well-
established role in the pre-and post-treatment staging of Hodgkin lymphoma (HL), however …

Interim positron emission tomography scan in Hodgkin lymphoma: definitions, interpretation rules, and clinical validation

A Gallamini, F Fiore, R Sorasio… - Leukemia & lymphoma, 2009 - Taylor & Francis
[18F]-Fluoro-2-deoxy-d-glucose positron emission tomography (18F-FDG PET) scan
performed early during the therapy for Hodgkin lymphoma (HL) has a high prognostic value …

Interim 18F-FDG PET SUVmax reduction is superior to visual analysis in predicting outcome early in Hodgkin lymphoma patients

C Rossi, S Kanoun, A Berriolo-Riedinger… - Journal of Nuclear …, 2014 - Soc Nuclear Med
PET performed after 2 cycles of chemotherapy (PET2) allows prediction of outcome in most
patients with Hodgkin lymphoma (HL). Visual analysis using a 5-point scale was proposed …

Early interim 18F-FDG PET in Hodgkin's lymphoma: evaluation on 304 patients

PL Zinzani, L Rigacci, V Stefoni, A Broccoli… - European journal of …, 2012 - Springer
Purpose The use of early (interim) PET restaging during first-line therapy of Hodgkin's
lymphoma (HL) in clinical practice has considerably increased because of its ability to …

[HTML][HTML] PET-guided treatment of early-stage favorable Hodgkin lymphoma: final results of the international, randomized phase 3 trial HD16 by the German Hodgkin …

M Fuchs, H Goergen, C Kobe, H Eich, C Baues, R Greil… - Blood, 2018 - Elsevier
Background. Combined modality treatment (CMT) consisting of two cycles of ABVD
(doxorubicin, bleomycin, vinblastine, dacarbazine) and 20 Gy of involved-field radiotherapy …

Interim FDG-PET in Hodgkin lymphoma: a compass for a safe navigation in clinical trials?

A Gallamini, L Kostakoglu - Blood, The Journal of the American …, 2012 - ashpublications.org
Despite the rewarding results achieved in the treatment of Hodgkin lymphoma (HL),
concerns have been raised regarding the long-term complications induced by therapy …

PET-adapted omission of radiotherapy in early stage Hodgkin lymphoma—a systematic review and meta-analysis

MT Sickinger, B von Tresckow, C Kobe… - Critical reviews in …, 2016 - Elsevier
Background Hodgkin lymphoma (HL) is one of the most common malignancies in young
adults and one of the most curable cancers worldwide. With interim PET-scan, HL treatment …

The role of FDG-PET in defining prognosis of Hodgkin lymphoma for early-stage disease

AM Evens, L Kostakoglu - Blood, The Journal of the American …, 2014 - ashpublications.org
Given the excellent survival rates for early-stage Hodgkin lymphoma (HL), the young age of
many patients, and concerns regarding acute and late treatment-related toxicities, there is a …