Therapeutic efficacy of a bivalent inhibitor of prostate-specific membrane antigen labeled with 67Cu
LE McInnes, C Cullinane, PD Roselt… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Radionuclide therapy targeting prostate-specific membrane antigen (PSMA) is promising for
prostate cancer. We previously reported a ligand, 64Cu-CuSarbisPSMA, featuring 2 lysine …
prostate cancer. We previously reported a ligand, 64Cu-CuSarbisPSMA, featuring 2 lysine …
[131I] MIP-1375, a small molecule prostate-specific membrane antigen (PSMA) inhibitor for targeted therapy of prostate cancer (PCa)
S Hillier, R Merkin, K Maresca, C Zimmerman, J Barrett… - 2011 - Soc Nuclear Med
361 Objectives [123 I] MIP-1072,(S)-2-(3-((S)-1-carboxy-5-(4-[123 I] iodobenzylamino)
pentyl) ureido) pentanedioic acid is a high affinity ligand for PSMA (Can Res 2009) which …
pentyl) ureido) pentanedioic acid is a high affinity ligand for PSMA (Can Res 2009) which …
[131I] MIP-1466, a small molecule prostate-specific membrane antigen (PSMA) inhibitor for targeted radiotherapy of prostate cancer (PCa)
S Hillier, K Rubino, K Maresca, J Marquis, M Tesson… - 2012 - Soc Nuclear Med
170 Objectives [123 I] MIP-1095,(S)-2-(3-((S)-1-carboxy-5-(3-(4-iodophenyl) ureido) pentyl)
ureido) pentanedioic acid, a high affinity ligand for PSMA (Can Res 2009), has been shown …
ureido) pentanedioic acid, a high affinity ligand for PSMA (Can Res 2009), has been shown …
99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen for molecular imaging of prostate cancer
SM Hillier, KP Maresca, G Lu, RD Merkin… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is highly expressed in prostate cancer, and
small-molecule radiopharmaceuticals targeting PSMA rapidly detect the location and extent …
small-molecule radiopharmaceuticals targeting PSMA rapidly detect the location and extent …
Radiolabeled Small-Molecule Ligands for Prostate-Specific Membrane Antigen: In vivo Imaging in Experimental Models of Prostate Cancer
Purpose: Prostate-specific membrane antigen (PSMA) is a cell surface protein that is
overexpressed in prostate cancer, including hormone-refractory and metastatic disease. Our …
overexpressed in prostate cancer, including hormone-refractory and metastatic disease. Our …
99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen: pharmacokinetics and biodistribution studies in healthy subjects and patients with …
S Vallabhajosula, A Nikolopoulou… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is a well-established target for developing
radiopharmaceuticals for imaging and therapy of prostate cancer (PCa). We have recently …
radiopharmaceuticals for imaging and therapy of prostate cancer (PCa). We have recently …
Albumin-binding PSMA ligands: implications for expanding the therapeutic window
JM Kelly, A Amor-Coarasa, S Ponnala… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Despite significant gains in the treatment of metastatic castration-resistant prostate cancer by
radioligands targeting prostate-specific membrane antigen (PSMA), 30% of patients never …
radioligands targeting prostate-specific membrane antigen (PSMA), 30% of patients never …
PSMA-GCK01: a generator-based 99mTc/188Re theranostic ligand for the prostate-specific membrane antigen
J Cardinale, FL Giesel, C Wensky… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) theranostics have been introduced with 68Ga
and 177Lu, the most used radionuclides. However, 188Re is a well-known generator-based …
and 177Lu, the most used radionuclides. However, 188Re is a well-known generator-based …
Recent developments of prostate-specific membrane antigen (PSMA)-specific radiopharmaceuticals for precise imaging and therapy of prostate cancer: an overview
SM Okarvi - Clinical and Translational Imaging, 2019 - Springer
Despite significant research activities and subsequent progress made in the fight against
cancer over the last few decades, prostate cancer remains a major health-related problem …
cancer over the last few decades, prostate cancer remains a major health-related problem …
New PSMA-Targeting Ligands: Transformation from Diagnosis (Ga-68) to Radionuclide Therapy (Lu-177)
Z Zha, SR Choi, L Li, R Zhao, K Ploessl… - Journal of Medicinal …, 2022 - ACS Publications
Prostate-specific membrane antigen (PSMA) is a promising target for the diagnosis and
radionuclide therapy of prostate cancer. This study reports conversion of a previously …
radionuclide therapy of prostate cancer. This study reports conversion of a previously …
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