Technetium-99m-sulfur colloid liver-spleen scans have been performed in a series of 11
children with sickle cell anemia and compared with series of children with clinically normal …

Abstract Observation of Howell—Jolly bodies in the blood of children with sickle-cell anemia
suggested the paradox of splenic hypofunction despite clinical splenomegaly. Spleen scans …

RESULTS 7. Incidence of S'lenomegalj. Of 115 patients with sickle cell anemia, twenty-one,
or 18 per cent, had splenomegaly.(Table I.) Fourteen patients, or two-thirds of those with …

Functional hyposplenism, as documented by technetium 99 metastable sulfur colloid spleen
scan and increased pocked erythrocyte count (also known as a pit count), is well described …

A prospective radiological and haematological study of 182 patients with homozygous sickle
cell anaemia has been undertaken to assess the prevalence and pattern of splenic …

Sickle cell patients develop splenic dysfunction early in the course of their disease as shown
by failure to visualize the organ on technetium‐99m colloid scintigraphy. However …

The spleen was assessed in 10 patients with sickle cell disease studied with computed
tomography (CT) for abdominal pain and/or unexplained fever. Patients with homozygous …

1. Studies of splenic function were carried out on patients with sickle-cell diseases by the
measurement of the clearance of autologous heat-damaged 99mTc-labelled erythrocytes …

The presence of hypersplenism and functional asplenia occurring concomitantly in a child
with sickle cell anemia prompted a study of the splenic platelet reservoir in this …

Splenic function in patients with sickle B+(SB+) thalassemia has been poorly documented.
We evaluated the clinical course and splenic function in 12 children with SB+ thalassemia …