Compared with the recent advancements in radiohalogenated Arg-Gly-Asp (RGD) peptides
for αvβ3-targeted imaging, there has been limited success with 99mTc-labeled RGD …

The αVβ3 integrin plays an important role in metastasis and tumor-induced angiogenesis.
Targeting with radiolabeled ligands of the αVβ3 integrin may provide information about the …

This study sought to evaluate [99mTc (HYNIC-Galacto-RGD2)(tricine)(TPPTS)](99mTc-
Galacto-RGD2: HYNIC= 6-hydrazinonicotinyl; Galacto-RGD2= Glu [cyclo [Arg-Gly-Asp-d …

To develop a companion set of RGD-based agents for diagnostic and radiotherapeutic
purposes, facile incorporation of 99mTc (CO) 3 or 188Re (CO) 3 into the same precursor …

INTRODUCTION: Radiolabeled RGD peptides that specifically target integrin ανβ3 have
great potential in early tumor detection through noninvasive monitoring of tumor …

Despite the recent development of various radiolabeled Arg-Gly-Asp (RGD) peptides for
imaging the αvβ3 integrin receptor, relatively little attention has been focused on the ability …

The Arg–Gly–Asp (RGD) peptide shows a high affinity for αvβ3 integrin, which is
overexpressed in new tumor blood vessels and many types of tumor cells. The radiolabeled …

This study was aimed to develop a glycopeptide (GP) to be used as a carrier for anti-cancer
drug delivery. GP was synthesized by conjugating glutamate peptide and chitosan using …

The cell adhesion molecule integrin αvβ3 is an important player in the process of
angiogenesis. In the last decades, a series of radiolabeled Arg-Gly-Asp (RGD) peptides …

αvβ3 integrins play an important role in angiogenesis and cell migration in cancer and are
highly expressed on the activated endothelial cells of newly formed blood vessels. Here, we …