89Zr-labeled anti-PD-L1 antibody PET monitors gemcitabine therapy-induced modulation of tumor PD-L1 expression
KH Jung, JW Park, JH Lee, SH Moon… - Journal of Nuclear …, 2021 - Soc Nuclear Med
We developed an 89Zr-labeled anti–programmed death ligand 1 (anti-PD-L1) immune PET
that can monitor chemotherapy-mediated modulation of tumor PD-L1 expression in living …
that can monitor chemotherapy-mediated modulation of tumor PD-L1 expression in living …
Molecular imaging of PD-L1 expression and dynamics with the adnectin-based PET tracer 18F-BMS-986192
TS Stutvoet, EL van der Veen, A Kol… - Journal of Nuclear …, 2020 - Soc Nuclear Med
18F-BMS-986192, an adnectin-based human programmed cell death ligand 1 (PD-L1)
tracer, was developed to noninvasively determine whole-body PD-L1 expression by PET …
tracer, was developed to noninvasively determine whole-body PD-L1 expression by PET …
Optimizing Immuno-PET imaging of tumor PD-L1 expression: pharmacokinetic, Biodistribution, and Dosimetric comparisons of 89Zr-labeled anti-PD-L1 antibody …
A Bouleau, H Nozach, S Dubois… - Journal of Nuclear …, 2022 - Soc Nuclear Med
PET imaging of programmed cell death ligand 1 (PD-L1) may help to noninvasively predict
and monitor responses to anti–programmed cell death 1/anti-PD-L1 immunotherapies. In …
and monitor responses to anti–programmed cell death 1/anti-PD-L1 immunotherapies. In …
Synthesis and biologic evaluation of a novel 18F-labeled adnectin as a PET radioligand for imaging PD-L1 expression
The programmed death protein (PD-1) and its ligand (PD-L1) play critical roles in a
checkpoint pathway cancer cells exploit to evade the immune system. A same-day PET …
checkpoint pathway cancer cells exploit to evade the immune system. A same-day PET …
[HTML][HTML] Quantitative PET imaging of PD-L1 expression in xenograft and syngeneic tumour models using a site-specifically labelled PD-L1 antibody
C Christensen, LK Kristensen, MZ Alfsen… - European Journal of …, 2020 - Springer
Purpose Despite remarkable clinical responses and prolonged survival across several
cancers, not all patients benefit from PD-1/PD-L1 immune checkpoint blockade. Accordingly …
cancers, not all patients benefit from PD-1/PD-L1 immune checkpoint blockade. Accordingly …
[68Ga]Ga-AUNP-12 PET imaging to assess the PD-L1 status in preclinical and first-in-human study
Abstract Purpose PD-L1 PET imaging, as a non-invasive procedure, can perform a real-time,
dynamic and quantitative analysis of PD-L1 expression at tumor sites. In this study, we …
dynamic and quantitative analysis of PD-L1 expression at tumor sites. In this study, we …
[HTML][HTML] Development, characterization, and radiation dosimetry studies of 18F-BMS-986229, a 18F-labeled PD-L1 macrocyclic peptide PET tracer
J Kim, DJ Donnelly, T Tran, A Pena, AO Shorts… - Molecular Imaging and …, 2024 - Springer
Purpose In cancer immunotherapy, the blockade of the interaction between programmed
death-1 and its ligand (PD-1: PD-L1) has proven to be one of the most promising strategies …
death-1 and its ligand (PD-1: PD-L1) has proven to be one of the most promising strategies …
In vivo imaging of the programmed death ligand 1 by 18F PET
DEG Trotter, X Meng, P McQuade… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Programmed death ligand 1 (PD-L1) is an immune regulatory ligand that binds to the T-cell
immune check point programmed death 1. Tumor expression of PD-L1 is correlated with …
immune check point programmed death 1. Tumor expression of PD-L1 is correlated with …
Synthesis and preclinical evaluation of a 68Ga-labeled adnectin, 68Ga-BMS-986192, as a PET agent for imaging PD-L1 expression
S Robu, A Richter, D Gosmann, C Seidl… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Blocking the interaction of the immune checkpoint molecule programmed cell death protein-
1 and its ligand, PD-L1, using specific antibodies has been a major breakthrough for …
1 and its ligand, PD-L1, using specific antibodies has been a major breakthrough for …
In Vivo Evaluation and Dosimetry Estimate for a High Affinity Affibody PET Tracer Targeting PD-L1
DJ Rubins, X Meng, P McQuade, M Klimas… - Molecular Imaging and …, 2021 - Springer
Purpose In vivo imaging of programmed death ligand 1 (PD-L1) during immunotherapy
could potentially monitor changing PD-L1 expression and PD-L1 expression heterogeneity …
could potentially monitor changing PD-L1 expression and PD-L1 expression heterogeneity …