Radiolabeled RGD peptides that target αvβ3 integrin are promising tracers for imaging
tumor angiogenesis. Integrins and angiogenesis also play important roles in healing of …

αvβ3 integrins play an important role in angiogenesis and cell migration in cancer and are
highly expressed on the activated endothelial cells of newly formed blood vessels. Here, we …

The αVβ3 integrin plays an important role in metastasis and tumor-induced angiogenesis.
Targeting with radiolabeled ligands of the αVβ3 integrin may provide information about the …

Arginine-glycine-aspartic acid (RGD)–based imaging tracers allow specific imaging of
integrin αvβ3, a protein overexpressed during angiogenesis, leading to the possibility that it …

RGD (arginylglycylaspartic acid)–based imaging tracers allow specific imaging of integrin
αvβ3 expression, proteins overexpressed during angiogenesis; however, few studies have …

Purpose The molecular imaging of tumour neoangiogenesis currently represents a major
field of research for the diagnostic and treatment strategy of solid tumours. Endothelial cells …

Brain tumors are highly angiogenesis dependent. The cell adhesion receptor integrin αvβ3
is overexpressed in glioma and activated endothelial cells and plays an important role in …

Purpose RGD peptide-based radiotracers are well established as integrin α v β 3 imaging
probes to evaluate tumor angiogenesis or tissue remodeling after ischemia or infarction. In …

Integrin αvβ3 plays a significant role in tumor angiogenesis and is a receptor for the
extracellular matrix proteins with the exposed arginine-glycine-aspartic (RGD) tripeptide …

Overview The field of angiogenesis research is one of the most rapidly growing biomedical
disciplines. Great efforts are being made to develop anti-angiogenesis drugs for treatment of …