Investigating the therapeutic effects of co-grafting iPSCs and ventral mesencephalic tissue in Parkinsonian rats using [18F] FE-PE2I

KH Ma, LC Wang, LH Sun, YH Chen, C Halldin - 2019 - Soc Nuclear Med
1309 Objectives: Parkinson's disease (PD) is a neurodegenerative disorder characterized
by a severe loss of dopaminergic neurons in substantia nigra pars compacta. Clinically …

Evaluating the allograft effects of Sertoli cells and embryonic VM tissues in a Parkinsonian rat model using [18F] FE-PE2I/animal-PET

CY Cheng, YT Jhao, TK Chou, SJ Weng, YY Huang… - 2017 - Soc Nuclear Med
271 Objectives: Parkinson's disease (PD) is a neurodegenerative disorder characterized by
the degeneration of dopaminergic neurons in substantia nigra pars compata. Currently, the …

Measuring neuroinflammation in hemiparkinsonian rhesus treated with iPSC-derived dopaminergic neuronal grafts using [18F] FEPPA PET

M Zammit, M Olsen, M Slesarev, K Fuchs, S Vermilyea… - 2019 - Soc Nuclear Med
182 Background: Cell replacement with induced pluripotent stem cell-derived midbrain
dopaminergic neuronal grafts (iPSC-mDA) is a promising therapeutic strategy for …

Improvement of dopamine transporter binding after bone marrow mesenchymal stem cell therapy in a rat model of Parkinson's disease: Small animal PET studies with …

BN Park, K Lee, JK Yoon, YS An - 2014 - Soc Nuclear Med
467 Objectives This study was performed to evaluate the effects of intravenously
transplanted rat bone marrow-derived mesenchymal stem cells (BMSCs) in a rat model of …

Assessment of tumorigenicity and efficacy of transplantation therapy with ESC-derived neural cells by PET imaging

T Kawasaki, D Doi, A Morizane, T Kikuchi, T Hayashi… - 2013 - Soc Nuclear Med
1739 Objectives Recent advancement in embryonic stem cell (ESC) has led to the
expectation of regenerative therapy with transplantation for Parkinson9s disease (PD) which …

[HTML][HTML] The effect of Sertoli cells on xenotransplantation and allotransplantation of ventral mesencephalic tissue in a rat model of Parkinson's disease

YT Jhao, CH Chiu, CFF Chen, TK Chou, YW Lin, YT Ju… - Cells, 2019 - mdpi.com
Intra-striatal transplantation of fetal ventral mesencephalic (VM) tissue has a therapeutic
effect on patients with Parkinson's disease (PD). Sertoli cells (SCs) possess immune …

In vivo PET imaging of implanted cells in a Parkinson's disease rat model

W Ruimin, G Zhe, Z Jinming, S Li, S Aijia… - Chinese Journal of …, 2008 - osti.gov
Objective: It is a major hurdle for the researchers to mornitor the implanted cells
differentiation in vivo. This study was designed as a proof of concept of the feasibility to track …

In vivo imaging and evaluation of therapeutic effect of the neural stem cell treatment in 6-OHDA induced mouse model of Parkinsons disease

임형준 - 2015 - s-space.snu.ac.kr
Transplantation of neural stem cells (NSCs) has been proposed and shown efficacy in
animal models of Parkinsons disease (PD) as a disease course modifying treatment. There …

18F-DOPA PET/CT xenograft evaluation in macacus monkey with chemically induced Parkinson

G Grassetto, E Tonini, A Massaro, MC Marzola, E Banti… - 2010 - Soc Nuclear Med
1770 Objectives To investigate the capability of 18F-DOPA dynamic PET/CT in evaluating
the success of neuronal staminal cells transplantation in the basal ganglia of macacus …

In vivo detection of monoaminergic degeneration in lipopolysaccharide-induced rat model of Parkinson's disease using 18F-FP-(+)-DTBZ (18F-AV-133) PET

W Zhang, D Jiang, F Xie, X Lu, M Li, Y Guan, C Zuo - 2018 - Soc Nuclear Med
198 Objectives: Intra-nigral injection of lipopolysaccharide (LPS) in rodent animals has been
established as one of the effective models to selectively replicate the inflammatory reaction …