Noninvasive nuclear imaging enables the in vivo quantification of striatal dopamine receptor expression and raclopride affinity in mice
K Fischer, V Sossi, A Schmid… - Journal of Nuclear …, 2011 - Soc Nuclear Med
The increasing use of genetically engineered mice as animal models of human disease in
biomedical research, latest advances in imaging technologies, and development of novel …
biomedical research, latest advances in imaging technologies, and development of novel …
Imaging of striatal dopamine D2 receptors with a PET system for small laboratory animals in comparison with storage phosphor autoradiography: a validation study …
S Nikolaus, R Larisch, M Beu, H Vosberg… - Journal of Nuclear …, 2001 - Soc Nuclear Med
Several groups have developed high-resolution PET systems and shown the feasibility of in
vivo studies on small laboratory animals. In this investigation, one of these systems was …
vivo studies on small laboratory animals. In this investigation, one of these systems was …
Measurement of striatal and thalamic dopamine D2 receptor binding with 11C-raclopride
J Hirvonen, S Aalto, V Lumme, K Någren… - Nuclear medicine …, 2003 - journals.lww.com
Abstract 11 C-Raclopride is a widely used positron emission tomography (PET) tracer for
measurement of striatal D 2 dopamine receptor binding characteristics. Recently, 11 C …
measurement of striatal D 2 dopamine receptor binding characteristics. Recently, 11 C …
[HTML][HTML] Limitations of SRTM, Logan graphical method, and equilibrium analysis for measuring transient dopamine release with [11C] raclopride PET
JM Sullivan, SJ Kim, KP Cosgrove… - American journal of …, 2013 - ncbi.nlm.nih.gov
Conventional PET methods to estimate [11 C] raclopride binding potential (BP ND) assume
that endogenous dopamine concentration does not change during the scan time. However …
that endogenous dopamine concentration does not change during the scan time. However …
Validity and reliability of extrastriatal [11C] raclopride binding quantification in the living human brain
Abstract [11 C] raclopride is a well established PET tracer for the quantification of dopamine
2/3 receptors (D 2/3 R) in the striatum. Outside of the striatum the receptor density is up to …
2/3 receptors (D 2/3 R) in the striatum. Outside of the striatum the receptor density is up to …
Measurement of dopamine D2 receptors in living human brain using [11C] raclopride with ultra-high specific radioactivity
Y Fujimura, H Ito, H Takahashi, F Yasuno… - Nuclear medicine and …, 2010 - Elsevier
INTRODUCTION: High specific radioactivity is preferable in the measurement of
neuroreceptor bindings with positron emission tomography (PET) because receptor …
neuroreceptor bindings with positron emission tomography (PET) because receptor …
Occupancy of dopamine D2 receptors in the mouse brain measured using ultra-high-resolution single-photon emission tomography and [123I]IBF
PD Acton, C Hou, MP Kung, K Plössl… - European Journal of …, 2002 - Springer
Functional imaging of small animals, such as mice and rats, using ultra-high-resolution
positron emission tomography (PET) and single-photon emission tomography (SPET) …
positron emission tomography (PET) and single-photon emission tomography (SPET) …
Parametric mapping of binding in human brain of D2 receptor ligands of different affinities
T Siessmeier, Y Zhou, HG Buchholz… - Journal of Nuclear …, 2005 - Soc Nuclear Med
11C-Raclopride has been widely used for PET studies of dopamine D2/3 receptors in
human brain. The long half-life of 18F may impart advantages to the novel moderate-affinity …
human brain. The long half-life of 18F may impart advantages to the novel moderate-affinity …
Reproducibility of Striatal and Thalamic Dopamine D2 Receptor Binding Using [11C]raclopride with High-Resolution Positron Emission Tomography
K Alakurtti, S Aalto, JJ Johansson… - Journal of Cerebral …, 2011 - journals.sagepub.com
Positron emission tomography (PET) imaging of small striatal brain structures such as the
ventral striatum (VST) has been hampered by low spatial resolution causing partial-volume …
ventral striatum (VST) has been hampered by low spatial resolution causing partial-volume …
18F-MCL-524, an 18F-labeled dopamine D2 and D3 receptor agonist sensitive to dopamine: a preliminary PET study
SJ Finnema, V Stepanov, R Nakao… - Journal of Nuclear …, 2014 - Soc Nuclear Med
PET has been used to examine changes in neurotransmitter concentrations in the living
brain. Pioneering PET studies on the dopamine system have used D2 and D3 receptor …
brain. Pioneering PET studies on the dopamine system have used D2 and D3 receptor …