Effects of elevated plasma glucose levels on FDG rate constants in mouse brain

KP Wong, X Zhang, W Sha, SC Huang - 2011 - Soc Nuclear Med
2060 Objectives To investigate the impact of variations in plasma glucose levels on the FDG
rate constants in mouse brain using intravenous (IV) and intraperitoneal (IP) injections …

Impact of nonsteady plasma glucose level on the calculated cerebral metabolic rates of glucose in mice

KP Wong, X Zhang, SC Huang - 2011 - Soc Nuclear Med
546 Objectives To investigate the accuracy of cerebral metabolic rate of glucose (CMRglc)
calculation in mice when the plasma glucose concentration (Cglc) is not constant during …

Normoglycemic plasma glucose levels affect F-18 FDG uptake in the brain

J Claeys, K Mertens, Y D'Asseler, I Goethals - Annals of nuclear medicine, 2010 - Springer
Objective The aim of this study was to investigate whether normoglycemic glucose
concentrations interfere with cerebral F-18 FDG uptake. Methods The analysis was based …

Arterial blood sampling changes the steady state of glucose in rats during FDG-PET

IB del Re, HM Wu - 2010 - Soc Nuclear Med
1745 Objectives Metabolic rate of glucose (MR) can be measured using quantitative FDG-
PET. The method assumes that plasma glucose is at steady state throughout the scan and a …

[HTML][HTML] Effect of various blood glucose levels on regional FDG uptake in the brain

I Sarikaya, AN Albatineh… - Asia Oceania Journal of …, 2020 - ncbi.nlm.nih.gov
Objective (s): Studies have mainly assessed the effect of hyperglycemia on 18 F-
fluorodeoxyglucose (FDG) uptake in the brain. In this study, we assessed the FDG uptake of …

Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography

H Toyama, M Ichise, JS Liow, KJ Modell… - Journal of Nuclear …, 2004 - Soc Nuclear Med
The purpose of this study was to evaluate the feasibility of absolute quantification of regional
cerebral glucose utilization (rCMRglc) in mice by use of 18F-FDG and a small animal PET …

Quantification of cerebral glucose metabolic rate in mice using 18F-FDG and small-animal PET

SY Amy, HD Lin, SC Huang, ME Phelps… - Journal of Nuclear …, 2009 - Soc Nuclear Med
The aim of this study was to evaluate various methods for estimating the metabolic rate of
glucose utilization in the mouse brain (cMRglc) using small-animal PET and reliable blood …

Brain glucose transport and phosphorylation under acute insulin-induced hypoglycemia in mice: an 18F-FDG PET study

MF Alf, JMN Duarte, R Schibli, R Gruetter… - Journal of Nuclear …, 2013 - Soc Nuclear Med
We addressed the questions of how cerebral glucose transport and phosphorylation change
under acute hypoglycemia and what the underlying mechanisms of adaptation are …

Measurement of cerebral glucose metabolic rates in the anesthetized rat by dynamic scanning with 18F-FDG, the ATLAS small animal PET scanner, and arterial blood …

K Shimoji, L Ravasi, K Schmidt… - Journal of Nuclear …, 2004 - Soc Nuclear Med
Rodent models and genetically altered mice have recently become available to study many
human diseases. A sensitive and accurate PET scanner for small animals would be useful to …

Effects of administration route, dietary condition, and blood glucose level on kinetics and uptake of 18F-FDG in mice

KP Wong, W Sha, X Zhang… - Journal of Nuclear …, 2011 - Soc Nuclear Med
The effects of dietary condition and blood glucose level on the kinetics and uptake of 18F-
FDG in mice were systematically investigated using intraperitoneal and tail-vein injection …