Current investigations of cell transplant therapies in damaged myocardium are limited by the
inability to quantify cell transplant survival in vivo. We describe how the labeling of cells with …

Transplantation of progenitor cells (PCs) has been shown to improve neovascularization
and left ventricular function after myocardial ischemia. The fate of transplanted PCs has …

Purpose A promising SPECT-based method for evaluating stem cells therapy uses 111 In-
labelled cells, transfected with a reporter gene. Cells are first transplanted to the infarct, and …

The evaluation of stem cell–mediated cardiomyoplasty by noninvasive in vivo imaging is
critical for its clinical application. We hypothesized that dual-tracer small-animal SPECT …

Background 99mTc sestamibi and 201Tl are tracers that allow equivalent detection of
myocardial infarction. However, because sestamibi does not undergo as much time …

In this work, we determined the minimum number of detectable 111 In-tropolone-labelled
bone-marrow-derived stem cells from the maximum activity per cell which did not affect …

Rest-redistribution 201TIimaging is currently being used for myocardial viability detection,
but the ideal parameters for territory classi fication have not yet been defined. Trie aim of this …

Objective. 99mTc-HL-91 (Prognox) is a potential new hypoxia-avid myocardial imaging
agent. The purpose of this study was to determine whether this tracer would demonstrate …

Background. To optimize the use of thallium 201 rest-redistribution study in Tl-
201/technetium 99m sestamibi dual-isotope single photon emission computed tomography …

revision accepted May 26, 1998. For correspondence or reprints contact: David K. Glover,
MD, University of Virginia, Experimental Cardiology Laboratory, Cardiology Division, Box …