The organ and voxel-based individual dosimetry using single measurement approach for patients with multiple cycle 177Lu-DOTATATE therapy
1580 Purpose: For dosimetry after 177 Lu-DOTATATE therapy, the sequential SPECT/CT
imaging is required to obtain time-integrated activity in interested region. This procedure …
imaging is required to obtain time-integrated activity in interested region. This procedure …
Planar Images-Based Internal Dosimetry using Patient-Specific Organ S-Value after 177Lu-DOTATATE Therapy
3198 Introduction: Post-therapeutic dosimetry after 177 Lu-DOTATATE is required for the
optimization of further therapy. The voxel-based dosimetry using sequential SPECT/CT …
optimization of further therapy. The voxel-based dosimetry using sequential SPECT/CT …
Accurate dosimetry with fewer scans: Evaluation of the Prior-Information Approach to 177Lu-DOTATATE dosimetry
N Cole, D Mirando, Y Dewaraja, A Nelson - 2022 - Soc Nuclear Med
2820 Introduction: A major roadblock to dosimetry adoption is the burden of multiple image
acquisitions over several days. This study evaluates the accuracy of a single-timepoint …
acquisitions over several days. This study evaluates the accuracy of a single-timepoint …
Is it possible to achieve accurate dosimetry with a single 24-hour SPECT/CT post-administration of 177Lu-DOTATATE?
N Cole, D Mirando, T Stork, A Nelson - 2023 - Soc Nuclear Med
P37 Introduction: This study evaluates the feasibility of single-timepoint dosimetry (STPD) for
radiopharmaceutical therapy with a 24-hour SPECT/CT. There are often limitations in …
radiopharmaceutical therapy with a 24-hour SPECT/CT. There are often limitations in …
[HTML][HTML] Patient-specific dosimetry adapted to variable number of SPECT/CT time-points per cycle for Lu-DOTATATE therapy
L Vergnaud, AL Giraudet, A Moreau, J Salvadori… - EJNMMI physics, 2022 - Springer
Background The number of SPECT/CT time-points is important for accurate patient dose
estimation in peptide receptor radionuclide therapy. However, it may be limited by the …
estimation in peptide receptor radionuclide therapy. However, it may be limited by the …
Feasibility and reliability assessment of single imaging time-point for organ and tumour dosimetry following 177Lu-DOTATATE PRRT
A Konuparamban, A Nautiyal, A Jha, T Srichandan… - 2022 - Soc Nuclear Med
2817 Introduction: 177 Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) has
become a popular treatment option for neuroendocrine tumours (NETs) in recent years …
become a popular treatment option for neuroendocrine tumours (NETs) in recent years …
177Lu-DOTATATE Dosimetry for Normal Organs and Tumors with Multiple Voxel S-Value Approach
1568 Purpose: 177 Lu-DOTATATE therapy is regarded as a proper option for
neuroendocrine tumor (NET) because 177 Lu has good targeting performance and suitable …
neuroendocrine tumor (NET) because 177 Lu has good targeting performance and suitable …
Patient level dosimetry for radionuclide therapy: proof of concept for patients receiving 177Lu-DOTATATE
1632 Objectives: For peptide receptor radionuclide therapy, dosimetry of tumors (targets)
and healthy structures (organs at risk) is often determined at a population level. Patients …
and healthy structures (organs at risk) is often determined at a population level. Patients …
Simplified image‐based dosimetry using planar images and patient‐specific S‐values
Background Single time point measurement approach and hybrid dosimetry were proposed
to simplify the dosimetry process. It is anticipated that utilizing patient‐specific S‐value …
to simplify the dosimetry process. It is anticipated that utilizing patient‐specific S‐value …
Single-time-point imaging for dosimetry after [177Lu] Lu-DOTATATE: accuracy of existing methods and novel data-driven models for reducing sensitivity to time-point …
C Wang, AB Peterson, KK Wong… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Estimation of the time-integrated activity (TIA) for dosimetry from imaging at a single time
point (STP) facilitates the clinical translation of dosimetry-guided radiopharmaceutical …
point (STP) facilitates the clinical translation of dosimetry-guided radiopharmaceutical …
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