The organ and voxel-based individual dosimetry using single measurement approach for patients with multiple cycle 177Lu-DOTATATE therapy

KM Kim, MS Lee, M seok Suh, GJ Cheon, JS Lee - 2021 - Soc Nuclear Med
1580 Purpose: For dosimetry after 177 Lu-DOTATATE therapy, the sequential SPECT/CT
imaging is required to obtain time-integrated activity in interested region. This procedure …

Planar Images-Based Internal Dosimetry using Patient-Specific Organ S-Value after 177Lu-DOTATATE Therapy

KM Kim, M Suh, GJ Cheon, KW Kang, JS Lee - 2022 - Soc Nuclear Med
3198 Introduction: Post-therapeutic dosimetry after 177 Lu-DOTATATE is required for the
optimization of further therapy. The voxel-based dosimetry using sequential SPECT/CT …

Accurate dosimetry with fewer scans: Evaluation of the Prior-Information Approach to 177Lu-DOTATATE dosimetry

N Cole, D Mirando, Y Dewaraja, A Nelson - 2022 - Soc Nuclear Med
2820 Introduction: A major roadblock to dosimetry adoption is the burden of multiple image
acquisitions over several days. This study evaluates the accuracy of a single-timepoint …

Is it possible to achieve accurate dosimetry with a single 24-hour SPECT/CT post-administration of 177Lu-DOTATATE?

N Cole, D Mirando, T Stork, A Nelson - 2023 - Soc Nuclear Med
P37 Introduction: This study evaluates the feasibility of single-timepoint dosimetry (STPD) for
radiopharmaceutical therapy with a 24-hour SPECT/CT. There are often limitations in …

[HTML][HTML] Patient-specific dosimetry adapted to variable number of SPECT/CT time-points per cycle for Lu-DOTATATE therapy

L Vergnaud, AL Giraudet, A Moreau, J Salvadori… - EJNMMI physics, 2022 - Springer
Background The number of SPECT/CT time-points is important for accurate patient dose
estimation in peptide receptor radionuclide therapy. However, it may be limited by the …

Feasibility and reliability assessment of single imaging time-point for organ and tumour dosimetry following 177Lu-DOTATATE PRRT

A Konuparamban, A Nautiyal, A Jha, T Srichandan… - 2022 - Soc Nuclear Med
2817 Introduction: 177 Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) has
become a popular treatment option for neuroendocrine tumours (NETs) in recent years …

177Lu-DOTATATE Dosimetry for Normal Organs and Tumors with Multiple Voxel S-Value Approach

KM Kim, MS Lee, M seok Suh, TH Tan, HSMS Selvam… - 2021 - Soc Nuclear Med
1568 Purpose: 177 Lu-DOTATATE therapy is regarded as a proper option for
neuroendocrine tumor (NET) because 177 Lu has good targeting performance and suitable …

Patient level dosimetry for radionuclide therapy: proof of concept for patients receiving 177Lu-DOTATATE

SS James, E Padilla-Morales, E Bergsland, T Hope - 2019 - Soc Nuclear Med
1632 Objectives: For peptide receptor radionuclide therapy, dosimetry of tumors (targets)
and healthy structures (organs at risk) is often determined at a population level. Patients …

Simplified image‐based dosimetry using planar images and patient‐specific S‐values

KM Kim, M Suh, GJ Cheon, MS Lee, JS Lee - Medical Physics, 2024 - Wiley Online Library
Background Single time point measurement approach and hybrid dosimetry were proposed
to simplify the dosimetry process. It is anticipated that utilizing patient‐specific S‐value …

Single-time-point imaging for dosimetry after [177Lu] Lu-DOTATATE: accuracy of existing methods and novel data-driven models for reducing sensitivity to time-point …

C Wang, AB Peterson, KK Wong… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Estimation of the time-integrated activity (TIA) for dosimetry from imaging at a single time
point (STP) facilitates the clinical translation of dosimetry-guided radiopharmaceutical …