Noninvasive 89Zr-transferrin PET shows improved tumor targeting compared with 18F-FDG PET in MYC-overexpressing human triple-negative breast cancer

KE Henry, TR Dilling, D Abdel-Atti… - Journal of Nuclear …, 2018 - Soc Nuclear Med
The current standard for breast PET imaging is 18F-FDG. The heterogeneity of 18F-FDG
uptake in breast cancer limits its utility, varying greatly among receptor status …

[HTML][HTML] The role of PET/CT in breast cancer

B Hadebe, L Harry, T Ebrahim, V Pillay, M Vorster - Diagnostics, 2023 - mdpi.com
Female breast cancer has surpassed lung cancer as the most commonly diagnosed cancer
worldwide, with an estimated 2.3 million new cases (11.7%), followed by lung cancer …

Molecular imaging in breast cancer

D Miladinova - Nuclear Medicine and Molecular Imaging, 2019 - Springer
Breast cancer (BC) is the most common cancer among females with more than 2 million new
cases diagnosed worldwide in 2018. Although the prognosis in the majority of cases in the …

The evolving role of PET/CT in breast cancer

D Groheux, S Giacchetti, D Rubello… - Nuclear Medicine …, 2010 - journals.lww.com
Positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG-PET) has become
a standard imaging procedure in the management of malignant diseases including breast …

[HTML][HTML] A preclinical PET dual-tracer imaging protocol for ER and HER2 phenotyping in breast cancer xenografts

M Paquette, S Phoenix, C Lawson, B Guérin… - EJNMMI research, 2020 - Springer
Background Nuclear medicine is on the constant search of precision radiopharmaceutical
approaches to improve patient management. Although discordant expression of the …

Annotating MYC status with 89Zr-transferrin imaging

JP Holland, MJ Evans, SL Rice, J Wongvipat… - Nature medicine, 2012 - nature.com
A noninvasive technology that quantitatively measures the activity of oncogenic signaling
pathways could have a broad impact on cancer diagnosis and treatment with targeted …

Use of 64Cu-DOTA-trastuzumab PET to predict response and outcome of patients receiving trastuzumab emtansine for metastatic breast cancer: a pilot study

JE Mortimer, JR Bading, PH Frankel… - Journal of Nuclear …, 2022 - Soc Nuclear Med
We hypothesized that functional imaging with 64Cu-DOTA-trastuzumab PET/CT would
predict the response to the antibody–drug conjugate trastuzumab–emtansine (T-DM1) …

[PDF][PDF] FDG-PET and beyond: molecular breast cancer imaging

A Quon, SS Gambhir - Journal of clinical oncology, 2005 - stati34521.narod.ru
Positron emission tomography (PET) scanning has gained widespread acceptance for the
diagnosis, staging, and management of a variety of malignancies, including breast cancer …

64Cu-DOTA-trastuzumab PET imaging in patients with HER2-positive breast cancer

K Tamura, H Kurihara, K Yonemori… - Journal of Nuclear …, 2013 - Soc Nuclear Med
The purpose of this study was to determine the safety, distribution, internal dosimetry, and
initial human epidermal growth factor receptor 2 (HER2)–positive tumor images of 64Cu …

18F-FDG small-animal PET/CT differentiates trastuzumab-responsive from unresponsive human breast cancer xenografts in athymic mice

K McLarty, A Fasih, DA Scollard, SJ Done… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Breast cancers (BCs) with high human epidermal growth factor receptor type 2 (HER2)
expression are most likely to respond to trastuzumab; however, the mechanisms of action of …