Parkinson's disease (PD) is associated with aberrant innate immune responses, including
microglial activation and infiltration of peripheral myeloid cells into the central nervous …

Neuroinflammation is a key pathologic hallmark of numerous neurologic diseases, however,
its exact role in vivo is yet to be fully understood. PET imaging enables investigation …

Neuroinflammation through enhanced innate immunity is thought play a role in the
pathogenesis of Parkinson's disease (PD). Methods for monitoring neuroinflammation in …

Background The 18-kDa translocator protein (TSPO) is an important target for assessing
neuroimmune function in brain with positron-emission tomography (PET) imaging. The goal …

Neuroinflammation through enhanced innate immunity is thought play a role in the
pathogenesis of Parkinson's disease (PD). Methods for monitoring neuroinflammation in …

The adaptive immune system, particularly T cells and more recently B cells, is considered to
play a major role in the pathogenesis of multiple sclerosis (MS). In addition to adaptive …

Neuroinflammation involves the activation of microglia and astrocytes, release of cytokines
and chemokines, production of reactive oxygen species, and oftentimes the infiltration of …

Neuroinflammation plays a major role in the etiopathology of neurodegenerative diseases,
including Alzheimer and Parkinson diseases, frontotemporal lobar degeneration, and …

This study investigated whether the second-generation translocator protein 18kDa (TSPO)
radioligand,[18F]-FEPPA, could be used in neurodegenerative parkinsonian disorders as a …

There is emerging interest in understanding the role of the neuroimmune system in the
pathophysiology of neurodegenerative and psychiatric diseases. 1, 2 Neuroinflammation is …