PET imaging in a mouse model of traumatic brain injury with [18F] 3F4AP
K Ramos-Torres, E Mandeville, K Takahashi… - 2020 - Soc Nuclear Med
154 Objectives: Traumatic brain injury (TBI) results from energy transmission to the brain,
disrupting its normal function 1. While clinical TBI is markedly heterogenous, the primary …
disrupting its normal function 1. While clinical TBI is markedly heterogenous, the primary …
Quantitative comparison of [18F] 3F4AP with MRI and other PET radiotracers in a monkey with a prior traumatic brain injury
155 Introduction:[18 F] 3F4AP was recently developed for PET imaging of voltage-gated
potassium channels in the brain (K v 1 family) based on the multiple sclerosis drug 4 …
potassium channels in the brain (K v 1 family) based on the multiple sclerosis drug 4 …
PET imaging in a rat model of spinal cord injury with [18F] 3F4AP
K Ramos-Torres, S Conti, YP Zhou, K Takahashi… - 2023 - Soc Nuclear Med
P980 Introduction: Spinal cord injury (SCI) results in devastating loss of mobility, typically
resulting in life-long impairments to independence and quality of life. While some patients …
resulting in life-long impairments to independence and quality of life. While some patients …
First-in-human brain imaging with [18F] 3F4AP, a PET tracer developed for imaging demyelination
N Guehl, Y Sun, A Russo, K Ramos-Torres… - 2022 - Soc Nuclear Med
2485 Introduction:[18 F] 3F4AP is a radiofluorinated derivative of the multiple sclerosis drug
4-aminopyridine.[18 F] 3F4AP binds to K+ channels of demyelinated axons and has shown …
4-aminopyridine.[18 F] 3F4AP binds to K+ channels of demyelinated axons and has shown …
The radiological study of traumatic brain injury: an emphasis upon molecular imaging
2023 Introduction: 1. To review the clinical practices in the radiological assessment of
neurological trauma 2. To assess the value of functional imaging in the hyperacute, acute …
neurological trauma 2. To assess the value of functional imaging in the hyperacute, acute …
cGMP production of [18F] 3F4AP for human PET imaging
K Ramos-Torres, J Noel, D Vesper, P Rice… - 2021 - Soc Nuclear Med
1461 Objectives:[18 F] 3-fluoro-4-aminopyridine ([18 F] 3F4AP) is a PET radioligand for
imaging demyelinated lesions in the brain based on the multiple sclerosis (MS) drug 4 …
imaging demyelinated lesions in the brain based on the multiple sclerosis (MS) drug 4 …
PET Imaging of Neurodegeneration in Two Subjects With a History of Repetitive Trauma and Cognitive Decline
DO Okonkwo, RC Puffer, DS Minhas… - … Editor's Pick 2021, 2021 - books.google.com
Objective: To present results from a neuroimaging protocol for in vivo evaluation of TBI-
related of TBI. neurodegeneration in patients with early-onset cognitive decline and a history …
related of TBI. neurodegeneration in patients with early-onset cognitive decline and a history …
PET imaging for traumatic brain injury
JG Dubroff, AB Newberg - PET clinics, 2010 - pet.theclinics.com
With over 1.5 million annual incidences resulting in an estimated 50,000 deaths, 300,000
hospitalizations, 80,000 to 90,000 long-term disabled individuals and estimated costs at …
hospitalizations, 80,000 to 90,000 long-term disabled individuals and estimated costs at …
Evaluation of anesthesia effects on the brain uptake and metabolism of demyelination tracer [18F] 3F4AP
2956 Introduction:[18 F] 3-fluoro-4-aminopyridine ([18 F] 3F4AP) is a PET radioligand for
imaging demyelinated lesions in the central nervous system (CNS) based on the multiple …
imaging demyelinated lesions in the central nervous system (CNS) based on the multiple …
Imaging demyelination in multiple sclerosis with [18F] 3F4AP
P19 Introduction: MRI is the gold standard for imaging multiple sclerosis (MS) offering high
resolution and excellent sensitivity to focal demyelinating lesions. However, MRI struggles to …
resolution and excellent sensitivity to focal demyelinating lesions. However, MRI struggles to …