The aim of the study was to investigate the increase in myocardial 99mTc-
methoxyisobutylisonitrile (sestamibi) retention in humans during pharmacologic …

We developed a noninvasive method to quantitatively estimate the myocardial blood flow
(MBF) index and flow reserve (MFR) using dynamic and static data obtained with technetium …

Objectives. Development of the coronary pressure wire has facilitated the measurement of
fractional flow reserve (FFR) to assess the functional severity of coronary artery stenoses …

Background Myocardial uptake of either 201Tl or 99mTc-sestamibi (sestamibi) is known to
plateau at high coronary flow rates. However, few direct comparisons have been made …

The purpose of this study was to determine the blood clearance, myocardial uptake and
heart/lung and heart/liver ratios of technetium 99m methoxyisobutylisonitrile (99m Tc …

Dobutamine is used as an alternative to exercise in conjunction with 99mTc-sestamibi
SPECT perfusion imaging for detection of coronary artery disease. However, the use of …

Background Pharmacologic stress has been shown in animal studies to induce high
degrees of myocardial hyperemia. At these levels of myocardial blood flow, the myocardial …

This study was designed to assess the relationship between the distribution of the
monocationic 99m Tc-hexakis-2-methoxy, 2-methylpropylisonitrile (99m Tc-sestamibi) and …

The aim of this study was to assess whether a clinically relevant change in myocardial
sestamibi activity could be documented within the first 120 min following injection (pi). In 17 …

Background. Trimetazidine is an antiischemic drug protecting the myocardium from ischemic
damage through the preservation of mitochondrial oxidative metabolism, without any …