Sequential H215O PET studies in baboons: before and after amphetamine

JC Price, WC Drevets, J Ruszkiewicz… - Journal of Nuclear …, 2002 - Soc Nuclear Med
PET and 11C-raclopride have been used to assess dopamine activity in vivo using a
paradigm that involved d-amphetamine (AMPH)-induced endogenous dopamine release …

Striatal and extrastriatal dopamine release measured with PET and [18F] fallypride

M Slifstein, LS Kegeles, X Xu, JL Thompson… - Synapse, 2010 - Wiley Online Library
The amphetamine challenge, in which positron emission tomography (PET) or single photon
emission computed tomography radioligand binding following administration of …

PET measurement of endogenous neurotransmitter activity using high and low affinity radiotracers

JC Price, NS Mason, B Lopresti, D Holt… - … functional brain imaging …, 1998 - Elsevier
Functional imaging of the in vivo competition of dopamine-D 2 radioligands with
endogenous dopamine has provided indirect measures of dopamine activity. Binding …

[HTML][HTML] Limitations of SRTM, Logan graphical method, and equilibrium analysis for measuring transient dopamine release with [11C] raclopride PET

JM Sullivan, SJ Kim, KP Cosgrove… - American journal of …, 2013 - ncbi.nlm.nih.gov
Conventional PET methods to estimate [11 C] raclopride binding potential (BP ND) assume
that endogenous dopamine concentration does not change during the scan time. However …

Development of a simultaneous PET/microdialysis method to identify the optimal dose of 11C-raclopride for small animal imaging

WK Schiffer, DL Alexoff, C Shea, J Logan… - Journal of neuroscience …, 2005 - Elsevier
In the field of small animal positron emission tomography (PET), the assumptions underlying
human and primate kinetic models may not be sustained in rodents. That is, the threshold …

Imaging dopamine release with positron emission tomography (PET) and 11C-raclopride in freely moving animals

VD Patel, DE Lee, DL Alexoff, SL Dewey, WK Schiffer - Neuroimage, 2008 - Elsevier
We investigated an imaging strategy that provides simultaneous measurements of
radiotracer binding and behavior in awake, freely moving animals. In this strategy, animals …

Positron emission tomography imaging of amphetamine‐induced dopamine release in the human cortex: A comparative evaluation of the high affinity dopamine D2/3 …

R Narendran, WG Frankle, NS Mason, EA Rabiner… - Synapse, 2009 - Wiley Online Library
The use of PET and SPECT endogenous competition binding techniques has contributed to
the understanding of the role of dopamine in several neuropsychiatric disorders. An …

Measurement of Methylphenidate-Induced Change in Extrastriatal Dopamine Concentration using [11C]FLB 457 PET

AJ Montgomery, MC Asselin, L Farde… - Journal of Cerebral …, 2007 - journals.sagepub.com
[11C] FLB 457 is a very high-affinity radiotracer that allows the measurement of dopamine
D2/3 receptor availability in regions of the brain where densities are very low, such as the …

New rapid analysis method demonstrates differences in 6-[18F] fluoro-L-dopa plasma input curves with and without carbidopa and in hemi-MPTP lesioned monkeys

CA McLellan, DJ Doudet, T Brücke, TG Aigner… - International journal of …, 1991 - Elsevier
Kinetic modeling of the PET tracer 6-[18 F] fluoro-l-dopa ([18 F] Dopa), used to measure
presynaptic dopamine function, requires the accurate determination of the plasma input …

The Simplified Reference Tissue Model with 18F-Fallypride Positron Emission Tomography: Choice of Reference Region

K Ishibashi, CL Robertson, MA Mandelkern… - Molecular …, 2013 - journals.sagepub.com
The development of high-affinity radiotracers for positron emission tomography (PET) has
allowed for quantification of dopamine receptors in extrastriatal and striatal regions of the …