Loss of nigrostriatal neurons leading to dopamine depletion in the dorsal striatum is the
pathologic hallmark of Parkinson disease contributing to the primary motor symptoms of the …

We investigated the alteration of dopaminergic system in striata of Parkinson's disease (PD)
at different stages using positron emission tomography (PET),[11C] 2β-carbomethoxy-3β-(4 …

Purpose The aim of the study was to evaluate extrastriatal dopaminergic and serotonergic
pathways in patients with Parkinson's disease (PD) and dementia with Lewy bodies (DLB) …

Purpose Single-photon emission computed tomography (SPECT) with [123 I] FP-CIT is a
marker for loss of presynaptic dopamine transporters in the striatum in Parkinson's disease …

Parkinson's disease is characterized by degeneration of dopaminergic neurons, resulting in
loss of dopamine transporters in the striatum. Recently, the tracer 123l-/Vo)-fluoropropyl-2ß …

The aim of this study was to investigate the progression of dopaminergic hypofunction in
striatal subregions in Parkinson's disease (PD). We studied 12 patients with early PD and 11 …

Parkinson disease (PD), progressive supranuclear palsy (PSP), and multiple-system atrophy
(MSA) are known to affect dopaminergic neurons of the brain stem and striatum with different …

Purpose The aim of this study was to evaluate, by means of 123 I-FP-CIT SPECT, the effect
of chronic treatment with levodopa on striatal dopamine transporter (DAT) in patients with …

Aims: Definition of the regional pattern of dopamine transporter (DAT) dysfunction in
advanced Parkinson's disease (PD) and evaluation of a potential correlation between DAT …

Background Parkinson's disease (PD) affects the integrity of the dopamine and serotonin
system, and is characterized by a plethora of different symptoms, including cognitive …