Because of its intrinsic quantitative properties, PET permits measurement of myocardial
perfusion and metabolism in absolute terms (ie, mL/g/min). However, quantification has …

Quantification of myocardial perfusion with 82Rb has been difficult to achieve because of the
low signal-to-noise ratio of the dynamic data curves. This study evaluated the accuracy of …

Because the use of factor analysis has been proposed for extracting pure physiologic
temporal or spatial information from dynamic nuclear medicine images, factor analysis …

Physiological functions (eg, cerebral blood flow, glucose metabolism, and neuroreceptor
binding) can be investigated as parameters estimated by kinetic modeling using dynamic …

Derivation of the plasma time–activity curve in murine small-animal PET studies is a
challenging task when tracers that are sequestered by the myocardium are used, because …

The purpose of this study was to assess a 3-dimensional (3D)-only PET scanner (ECAT
EXACT3D) for its use in the absolute quantification of myocardial blood flow (MBF) using …

Accordingly, the aims of the present study were:(1) to evaluate in human subjects the
magnitude of the time dii ferences between the input function obtained from either the left …

The utilization of image-derived input functions is becoming common in quantitative PET
studies of the heart. Consequently, imaging protocols must be designed to sample both …

1663 MBF Quantification With PET produces high-quality images but sometimes shows a
mild defect in the lateral wall even in normal subjects (Figure 1). 17 Caution should therefore …

PET absolute myocardial blood flow (MBF) with H215O and 13NH3 are widely used in
clinical and research settings. However, their reproducibility with a 16-myocardial segment …