Myeloablative 131I-tositumomab radioimmunotherapy in treating non-Hodgkin's lymphoma: comparison of dosimetry based on whole-body retention and dose to …

JG Rajendran, AK Gopal, DR Fisher… - Journal of Nuclear …, 2008 - Soc Nuclear Med
Myeloablative radioimmunotherapy using 131I-tositumomab (anti-CD20) monoclonal
antibodies is an effective therapy for B-cell non-Hodgkin's lymphoma. The amount of …

High-dose 131I-tositumomab (anti-CD20) radioimmunotherapy for non-Hodgkin's lymphoma: adjusting radiation absorbed dose to actual organ volumes

JG Rajendran, DR Fisher, AK Gopal… - Journal of Nuclear …, 2004 - Soc Nuclear Med
Radioimmunotherapy (RIT) using 131I-tositumomab has been used successfully to treat
relapsed or refractory B-cell non-Hodgkin's lymphoma (NHL). Our approach to treatment …

A Phase II Study of Myeloablative I-131-Anti CD-20 (Tositumomab) Radioimmunotherapy and Autologous Hematopoietic Stem Cell Transplantation (ASCT) for Adults …

AK Gopal, JG Rajendran, TA Gooley, JM Pagel… - Blood, 2005 - Elsevier
The majority of patients with relapsed or refractory B-cell, non-Hodgkin's lymphoma (NHL)
are over 60 years of age, yet many are denied potentially curative high-dose regimens due …

Tumor-absorbed dose predicts progression-free survival following 131I-tositumomab radioimmunotherapy

YK Dewaraja, MJ Schipper, J Shen… - Journal of Nuclear …, 2014 - Soc Nuclear Med
The study aimed at identifying patient-specific dosimetric and nondosimetric factors
predicting outcome of non-Hodgkin lymphoma patients after 131I-tositumomab …

A practical methodology for patient release after tositumomab and 131I-tositumomab therapy

JA Siegel, S Kroll, D Regan… - Journal of Nuclear …, 2002 - Soc Nuclear Med
A methodology was developed determining patient releasability after radioimmunotherapy
with tositumomab and 131I-tositumomab for the treatment of non-Hodgkin's lymphoma …

The clinical importance of dosimetry in radioimmunotherapy with tositumomab and iodine I 131 tositumomab

RL Wahl - Seminars in oncology, 2003 - Elsevier
Radioimmunotherapy (RIT) is a promising emerging therapy for non-Hodgkin's lymphoma
and may ultimately prove useful in the treatment of other tumors. The most extensively …

Tositumomab and 131I therapy in non-Hodgkin's lymphoma

RL Wahl - Journal of Nuclear Medicine, 2005 - Soc Nuclear Med
Tositumomab and 131 I-tositumomab constitute a relatively new radioimmunotherapeutic
regimen for patients with CD20+ follicular non-Hodgkin's lymphoma (NHL). Currently, it is …

Organ dosimetry dose escalation of Yttrium 90 ibritumomab tiuxetan radioimmunotherapy (90Y IT) with stem cell transplantation (ASCT) in patients with non-Hodgkin's …

R Wahl, E Frey, B Kahl, S Piantadosi, J Bianco… - 2006 - Soc Nuclear Med
277 Objectives: Anti CD-20 Radioimmunotherapy is useful at non-myeloablative doses for
many patients with chemotherapy refractory low grade and transformed low grade …

Radioimmunotherapy with tositumomab and iodine-131 tositumomab for non-Hodgkin's lymphoma

B Andemariam, JP Leonard - Biologics: Targets and Therapy, 2007 - Taylor & Francis
With the success of targeted monoclonal antibody therapy in non-Hodgkin's lymphoma,
attempts were made to further improve efficacy through the addition of a radioisotope. A goal …

Radioimmunotherapy for non-Hodgkin's lymphoma

C Emmanouilides - Seminars in oncology, 2003 - Elsevier
Radioimmunotherapy (RIT) treatment for lymphoma is a novel targeted therapeutic
approach. Several years of development of radioimmunotherapeutic compounds came to …