Imaging of apoptosis

JF Tait - Journal of nuclear medicine, 2008 - Soc Nuclear Med
Cells can die by several pathways, such as accidental death, apoptosis, autophagy,
pyroptosis, and oncosis. These are important in normal physiology and many disease states …

In vivo imaging of apoptosis

FG Blankenberg - Cancer biology & therapy, 2008 - Taylor & Francis
Despite over a decade of intense investigation there is still no routine method for the clinical
imaging of apoptosis in oncologic patients. There have been multiple tracers proposed but …

Will imaging of apoptosis play a role in clinical care? A tale of mice and men

FG Blankenberg, HW Strauss - Apoptosis, 2001 - Springer
Programmed cell death (apoptosis) plays a role in the pathophysiology of many diseases
and in the outcome of treatment. Apoptosis is the likely mechanism behind the cytoreductive …

Apoptosis imaging: beyond annexin V

G Niu, X Chen - Journal of Nuclear Medicine, 2010 - Soc Nuclear Med
Induction of apoptosis is the primary mechanism through which most chemotherapies cause
tumor cell death. Early assessment of tumor response is required to manage patients in …

Imaging cell death in vivo

F Blankenberg, C Mari… - The Quarterly Journal of …, 2003 - search.proquest.com
A technique to image programmed cell death would be useful both in clinical care and in
drug development. The most widely studied agent for the in vivo study of apoptosis is …

The imaging of apoptosis with the radiolabeled annexin V: optimal timing for clinical feasibility

T Belhocine, N Steinmetz, C Li… - … in cancer research …, 2004 - journals.sagepub.com
In recent years, the imaging of drug-induced apoptosis has become one of the centers of
interest in experimental and clinical research. In particular, the accurate monitoring of …

Innovative strategies in in vivo apoptosis imaging

J Schoenberger, J Bauer, J Moosbauer… - Current medicinal …, 2008 - ingentaconnect.com
Apoptosis (programmed cell death) plays a key role in the pathogenesis of many disorders
including cerebral and myocardial ischemia, autoimmune and neurodegenerative diseases …

In vivo detection of apoptosis

FG Blankenberg - Journal of Nuclear Medicine, 2008 - Soc Nuclear Med
After several decades of debate, it is now widely acknowledged that apoptosis, also known
as programmed cell death, is central to homoeostasis and normal development and …

Recent advances in the imaging of programmed cell death

FG Blankenberg - Current pharmaceutical design, 2004 - ingentaconnect.com
A deficiency or an excess of programmed cell death (apoptosis) is an integral component of
autoimmune disorders, organ and bone marrow transplant rejection, and cancer. A …

[PDF][PDF] Imaging of apoptosis (programmed cell death) with 99mTc annexin V

FG Blankenberg, PD Katsikis, JF Tait… - Journal of Nuclear …, 1999 - Soc Nuclear Med
Results: Membrane-bound radiolabeled annexin V activity lin early correlated to total
fluorescence as observed by FITC annexin V flow cytometry in Jurkat T-cell cultures induced …