Depression is associated with systemic inflammation, and the systemic inflammation caused
by endotoxin administration elicits mild depressive symptoms such as fatigue and reduced …

Posttraumatic stress disorder (PTSD) is an anxiety disorder that occurs after exposure to a
traumatic event. This study aimed to investigate the neurobiologic changes before and after …

We investigated changes in behavior and brain glucose metabolism in a rat chronic mild
stress (CMS) model of depression. The CMS model has been used to mimic depression in …

Depression is associated with peripheral inflammation, but its link with brain microglial
activity remains unclear. In seven healthy males, we used repeated translocator protein …

Delirium is a common, serious, yet poorly understood syndrome. Growing evidence
suggests cerebral metabolism is fundamentally disturbed; however, it has not been …

In this study, the authors investigated the relationship between anxiety and regional cortical
metabolism in Alzheimer's disease. Using the Neuropsychiatric Inventory (NPI), the authors …

Alzheimer's disease (AD) is a brain disorder characterized by reduced cerebral glucose
metabolism (CMRgl) in several cortical regions. Evidence from neuropathology studies …

Systemic infection triggers a spectrum of metabolic and behavioral changes, collectively
termed sickness behavior, which while adaptive, can affect mood and cognition. In …

Introduction Delirium is associated with new onset dementia and accelerated cognitive
decline; however, its pathophysiology remains unknown. Cerebral glucose metabolism …

BACKGROUND: Secondary depression is common in the clinical oncology setting after
pancreatic cancer diagnosis, following which the patients have to face the fact that they have …