Quantitative assessment of Ge-68 breakthrough from a commercial titanium-dioxide based Ge-68/Ga-68 generator

J Sunderland, D Dick, M Schultz, G Watkins, L Sensoy - 2013 - Soc Nuclear Med
1186 Objectives To quantitatively assess Ge-68 breakthrough in the eluant of a commercial
Ge-68/Ga-68 generator used for routine Ga-68 DOTATOC production, and to measure …

Rapid Ge-68 breakthrough testing for 68Ge/68Ga portable generators

M Urdaneta, P Stepanov, D Beylin, R Probst… - 2013 - Soc Nuclear Med
1195 Objectives 68Ge/68Ga generators are a promising addition to the molecular imaging
clinic. They are portable and offer years of useful life, delivering tracers for high resolution …

Purification of production scale amounts of Ge-68 from irradiated gallium metal

J Fitzsimmons, L Mausner - 2014 - Soc Nuclear Med
102 Objectives Germanium-68 (Ge-68) is produced by proton irradiation of a gallium metal
target and purified by organic extraction with toluene or carbon tetrachloride. The Ge-68 is …

Quantitative determination of 68Ge breakthrough of 68Ge/68Ga generators via TLC

E Eppard, N Loktionova, F Roesch - 2013 - Soc Nuclear Med
1198 Objectives 68 Ge/68 Ga generators contain initial activities of 20, 30 or more mCi of 68
Ge, respectively 68 Ga. Breakthrough levels of 68 Ge are located between 10-4 and 10-2 …

Quick and efficient Ga-68 DOTATATE synthesis using direct eluate from Ge specific silica based Ge 68-Ga 68 generator

J Shukla, A Sood, B Mittal - 2012 - Soc Nuclear Med
1129 Objectives Ga-68 a positron emitter and available from Ge 68-Ga 68 generator. Ga 68-
DOTATATE, a somatostatin receptor (SSTR) analog, is mainly used for SSTR+ ve tumor …

Purification and Labeling Strategies for 68Ga from 68Ge/68Ga Generator Eluate

D Mueller, I Klette, RP Baum - … , Gallium-68, and Other Radionuclides: A …, 2013 - Springer
Abstract For successful labeling, 68 Ge/68 Ga generator eluate has to be concentrated (from
10 mL or more to less than 1 mL) and to be purified of metallic impurities, especially Fe (III) …

Evaluation of a new Ge-68/Ga-68 generator for preparing high-purity radiopharmaceuticals for PET imaging

M Schultz, D McAlister, T Tewson, J Harvey, P Horwitz - 2008 - Soc Nuclear Med
1282 Objectives: A new Ge-68/Ga-68 generator was evaluated for producing Ga-68. Ga-68
is considered attractive for PET radiopharmaceuticals, but widespread use has been …

Qualification of 68Ge/68Ga generators: a comparison of organic matrix and tin oxide based generators

D Niculae, A Niculae - 2015 - Soc Nuclear Med
1055 Objectives The 68 Ga generators of a chromatographic type is a glass or
polypropylene column with a sorbent based on Al/Zr/Ti/Sn/Sb-oxides or organic matrix. The …

Characterization of organic matrix-based 68Ge/68Ga generators

I Tworowska, S Zamanian, E Delpassand - 2012 - Soc Nuclear Med
1474 Objectives Development of 68 Ge/68 Ga generator has increased interest in clinical
applications of 68 Ga PET agents that can be labeled and prepared on-site and on-demand …

Instantaneous quantitative determination of 68Ge breakthrough of 68Ge/68Ga generators

F Roesch, N Loktionova - 2012 - Soc Nuclear Med
1458 Objectives 68Ge/68Ga generators provide initial activities of 20, 30 or more mCi of
68Ge and 68Ga respectively. Breakthrough levels of 68Ge are between 10-4 and 10-2% in …