MATERIALS AND METhODS Radiopharmaceutical Preparation High specific activity [â€
231]-f3-CITwas prepared from the corresponding trimethylstannyl precursor (1)(Research …

Iodine-l23-13-CIT ([†23I] 2@ 3-carbomethoxy-3f3-(4-iodophenyl tropane) binds with high
affinity to dopamine(IC50= 1.6 nM) and serotonin (IC50= 3.78 nM) transporters and has …

Tri.-n-butyl-Sn-IPT@ p'i (MMG142E) vial was purged with a charcoal filter to trap the volatile
iodine. The solution was transferredfrom the vial to a test tube, and the vial was rinsed with …

333 Cedar St., New Haven, CT 06510. and Parkinson's disease patients for either outcome
measure. The reproducibility of left/right asymmetry indices and putamen-tocaudate ratios …

Abstract Iodine-123-2 beta-carbomethoxy-3 beta-(4-iodophenyl) tropane (beta-CIT) is a
useful SPECT tracer for imaging the dopamine transporter. Its slow kinetics, however …

Dopamine transporter (DAT) imaging with 123I-FP-CIT (123I-N-ω-fluoropropyl-2β-
carbomethoxy-3β-(4-iodophenyl) nortropane) SPECT is frequently used to detect loss of …

This study reports on the biodistribution and radiation dosimetry of iodine-123-labelled N-ω-
(flu-oropropyl)-2β-carbomethoxy-3β-(4-iodophenyl) tropane ([123 I] FP-CIT), a promising …

Loss of striatal dopamine (DA) transporters in Parkinson's disease (PD) has been accurately
assessed in vivo by single-photon emission tomography (SPET) studies using [123 I] β-CIT …

Imaging of Dopamine Transporters with Iodine-123- ß-CITand SPECT in Parkinson's
Disease Page 1 HUMAN STUDIES Nuclear Neurology Imaging of Dopamine Transporters …

β-CIT-FP [N-(3-fluoropropyl)-2β-carbomethoxy-3β-(4-iodophenyl) nortropane] is a cocaine
analogue with a high affinity for the dopamine transporter.[O-methyl-11C] β-CIT-FP ([11C] β …