Digital solid-state spect/ct quantitation of absolute 177Lu radiotracer concentration: in vivo and in vitro validation
JA Kennedy, R Lugassi, R Gill… - Journal of Nuclear …, 2020 - Soc Nuclear Med
The accuracy of 177Lu radiotracer concentration measurements using quantitative clinical
software was determined by comparing in vivo results for a digital solid-state cadmium-zinc …
software was determined by comparing in vivo results for a digital solid-state cadmium-zinc …
[HTML][HTML] In vivo quantification of 177Lu with planar whole-body and SPECT/CT gamma camera imaging
DL Bailey, TM Hennessy, KP Willowson, EC Henry… - EJNMMI physics, 2015 - Springer
Background Advances in gamma camera technology and the emergence of a number of
new theranostic radiopharmaceutical pairings have re-awakened interest in in vivo …
new theranostic radiopharmaceutical pairings have re-awakened interest in in vivo …
[HTML][HTML] Variability in lutetium-177 SPECT quantification between different state-of-the-art SPECT/CT systems
SMB Peters, SL Meyer Viol, NR van der Werf… - EJNMMI physics, 2020 - Springer
Background Quantitative SPECT imaging in targeted radionuclide therapy with lutetium-177
holds great potential for individualized treatment based on dose assessment. The …
holds great potential for individualized treatment based on dose assessment. The …
Absolute radiotracer concentration measurement using whole-body solid-state SPECT/CT technology: in vivo/in vitro validation
JA Kennedy, I Reizberg, R Lugassi… - Medical & Biological …, 2019 - Springer
The accuracy of recently approved quantitative clinical software was determined by
comparing in vivo/in vitro measurements for a solid-state cadmium-zinc-telluride SPECT/CT …
comparing in vivo/in vitro measurements for a solid-state cadmium-zinc-telluride SPECT/CT …
Gamma camera calibration and validation for quantitative SPECT imaging with 177Lu
M D'Arienzo, M Cazzato, ML Cozzella, M Cox… - Applied Radiation and …, 2016 - Elsevier
Over the last years 177 Lu has received considerable attention from the clinical nuclear
medicine community thanks to its wide range of applications in molecular radiotherapy …
medicine community thanks to its wide range of applications in molecular radiotherapy …
Quantitative SPECT/CT Imaging of 177Lu with In Vivo Validation in Patients Undergoing Peptide Receptor Radionuclide Therapy
Purpose The purpose of this study is to extend an established SPECT/CT quantitation
protocol to 177 Lu and validate it in vivo using urine samples, thus providing a basis for 3D …
protocol to 177 Lu and validate it in vivo using urine samples, thus providing a basis for 3D …
[HTML][HTML] Towards accurate 177Lu SPECT activity quantification and standardization using lesion-to-background voxel ratio
S Raskin, D Gamliel, D Abookasis, S Ben-Haim… - EJNMMI physics, 2023 - Springer
Background Conventional calibration of the gamma camera consists of the calculation of
calibration factors (CFs)(ratio of counts/cc and true concentration activity) as the function of …
calibration factors (CFs)(ratio of counts/cc and true concentration activity) as the function of …
Simplified patient-specific renal dosimetry in 177Lu therapy: a proof of concept
T Ligonnet, D Pistone, L Auditore, A Italiano, E Amato… - Physica Medica, 2021 - Elsevier
Purpose The aim of this proof-of-concept study is to propose a simplified personalized
kidney dosimetry procedure in 177 Lu peptide receptor radionuclide therapy (PRRT) for …
kidney dosimetry procedure in 177 Lu peptide receptor radionuclide therapy (PRRT) for …
[HTML][HTML] The effect of calibration factors and recovery coefficients on 177Lu SPECT activity quantification accuracy: a Monte Carlo study
K Ramonaheng, JA van Staden, H du Raan - EJNMMI physics, 2021 - Springer
Background Different gamma camera calibration factor (CF) geometries have been
proposed to convert SPECT data into units of activity concentration. However, no consensus …
proposed to convert SPECT data into units of activity concentration. However, no consensus …
Characterization of noise and resolution for quantitative 177Lu SPECT/CT with xSPECT Quant
J Tran-Gia, M Lassmann - Journal of Nuclear Medicine, 2019 - Soc Nuclear Med
Quantitative SPECT/CT imaging forms the basis for internal dosimetry in molecular
radiotherapies. While the conversion from counts to activity is typically based on conversion …
radiotherapies. While the conversion from counts to activity is typically based on conversion …