LDL was isQlatedfrom human hyperlipidemicplasma by sequential ultracentrifugation(14)
and dialyzed overnight against normal saline (pH 7.4) containing0. 1 mg/mbEDTA. Aliquots …

In patients suffering from clinically manifest atherosclerosis autologous LDL-labelling has
been done using 123 I. This technique allows localization of areas with an increased LDL …

The interaction of 111In-low-density lipoprotein (LDL) and 123I-LDL with human liver-
plasma membranes was investigated and compared. LDLs were isolated by sequential …

MATERIALS AND METHODS Preparation of low density lipoproteins LDL (density= 1.025 to
1.050 g/mb) were isolated from normal plasma by sequential flotation in the ultra centrifuge …

In an attempt to characterize the in vivo behavior of [" Tc] low density lipoprotein (LDL),
biodistribution studies were performed in normal and hypercholesterolemic (HC) rabbits. In …

MATERIALSAND METHODS Isolation and Derivatizatlon of Human LDL For these animal
studies, we electedto use human LDL rather than autologous rabbitor monkey LDL. Human …

99MTechnetium-labeled low density lipoprotein (99MTc-labeled LDL) was developed to
detect atherosclerosis by external imaging with the gamma scintillation camera (Lees, et al …

Low-density lipoprotein (LDL) labeled via direct iodination or via the radioiodinated
residualizing moiety tyramine-cellobiose (TC) were compared in rabbits as potential 123 I …

The feasibility of localizing human atherosclerotic plaques by gamma scintillation camera
external imaging with technetium-99m-labeled low density lipoproteins (99mTc-LDL) was …

In order to use the LDL receptor pathway to target radionuclides to cancer sites for imaging
and diagnostic purposes, a labeling procedure of LDL with 111In using the DTPA− bis …