616 Objectives: GluN2B is one of the most studied subunits of N‑methyl‑D‑aspartate
receptors (NMDARs), which are related to various central nervous system disorders and …

GluN2B‐containing NMDA receptors (NMDARs) play fundamental roles in learning and
memory, although they are also associated with various brain disorders. In this study, we …

263 Introduction: The GluN2B subunit-containing NMDA receptors are involved in numerous
pathologic conditions of the central nervous system, including Alzheimer's disease, ischemic …

The N-methyl-d-aspartate receptor (NMDAR) plays a crucial role in neurodegenerative
diseases such as Alzheimer disease and in the treatment of major depression by fast-acting …

1109 Objectives: As one of the most studied N-Methyl-D-aspartate receptor (NMDAR)
subunits, GluN2B is an important therapeutic target of drug discovery for the treatment of …

GluN2B subunit-containing N-methyl-d-aspartate (NMDA) receptors have been implicated in
various neurological disorders. Nonetheless, a validated fluorine-18 labeled positron …

The NMDA receptor GluN2B subunit is a target of interest in neuropsychiatric disorders but
to date there is no selective radiotracer available to quantify its availability in vivo. Here we …

The previously reported 11C-labeled GluN2B PET radioligand 11C-Me-NB1 served as a
starting point for derivatization and led to the successful development of a radiofluorinated …

P975 Introduction: Substantial efforts have been devoted to the development of PET
radiotracers for the GluN2B subunits of the NMDA receptor complex, with several 11 C-and …

Purpose There are currently no positron emission tomography (PET) radiotracers for the
GluN2B (NR2B) binding sites of brain N-methyl-d-aspartate (NMDA) receptors. In rats, the …