Influence of thyreotropin on mechanisms of apoptosis and radiation resistance of thyroid carcinoma cells

J Grosse, D Grimm, C Eilles, J Schoenberger - 2009 - Soc Nuclear Med
1589 Objectives Higher concentrations of thyreotropin (TSH) have to be considered as an
exogenic stress factor. Using two poorly differentiated thyroid carcinoma cell lines we …

Thyrotropin effects on ultraviolet radiation-dependent apoptosis in FRTL-5 cells

E Del Terra, A Francesconi, D Donnini, F Curcio… - Thyroid, 2003 - liebertpub.com
Apoptosis plays an important role within the endocrine system, particularly in the thyroid
gland, although little is known about its regulation in normal thyroids. Because thyrotropin …

Influence of thyrostatic drugs on cell vitality, necrosis and DNA damage after external irradiation of thyroid carcinoma cell culture

K Marx, D Moka, G Marx, C Kobe, H Schicha - 2006 - Soc Nuclear Med
631 Objectives: Studies on the effect of an external irradiation on cell vitality, cell necrosis
and the appearance of DNA damage. Especially, the potential radioprotective/antioxidative …

Changes of apoptosis, p53, and bcl-2 by irradiation in poorly differentiated thyroid carcinoma cell lines: a prognostic marker for the prospect of therapeutic success?

F Pohl, J Grosse, D Grimm, G Brockhoff, K Westphal… - Thyroid, 2010 - liebertpub.com
Background: Poorly differentiated thyroid carcinoma (PDTC) has an unfavorable prognosis.
Surgical management is the principal treatment approach. In addition, radioiodine treatment …

Thyroid hormones and regulation of cell reliability systems

AY Antipenko, YN Antipenko - Advances in Enzyme Regulation, 1994 - Elsevier
Data and arguments are presented that provide evidence of a role played by thyroid
hormones (TH) in cell reliability improvement. This role may be determined by synergistic TH …

Changes of expression level of the differentiation markers in papillary thyroid carcinoma under thyrotropin suppression therapy in vivo immunohistochemical detection …

K Tanaka, H Sonoo, Y Yamamoto… - Journal of surgical …, 2000 - Wiley Online Library
Abstract Background and Objectives Differences in the expression levels of Thyroglobulin
(Tg), Thyroid peroxidase (TPO) and thyrotropin receptor (TSH‐R) in primary and recurrent …

Effects of thyroxine on apoptosis and proliferation of mammary tumors

LE Zyla, R Cano, S Gómez, A Escudero, L Rey… - Molecular and Cellular …, 2021 - Elsevier
Hypothyroidism is a protective factor against breast cancer but long-term exposure or
overdoses of thyroid replacement therapy with thyroxine (T 4) may increase breast cancer …

[PDF][PDF] Thyroid-stimulating hormone receptor affects metastasis and prognosis in papillary thyroid carcinoma.

TR LI, X Su, WS Qiu, WC Chen, L Zou… - European Review for …, 2016 - europeanreview.org
OBJECTIVE: Although endocrine therapy of papillary thyroid carcinoma (PTC) by inhibiting
thyroid-stimulating hormone (TSH) has been used for many years, its mechanism of action is …

Thyrotropin prevents apoptosis by promoting cell adhesion and cell cycle progression in FRTL-5 cells

X Li, S Lu, E Miyagi, R Katoh, A Kawaoi - Endocrinology, 1999 - academic.oup.com
Apoptosis has been shown to be involved in endocrine tissue homeostasis as well as
regression due to hormone deprivation. The goal of this study was to induce apoptosis and …

The expression and significance of hormothyrin and thyroid hormone in thyroid cancer.

W Sang, L Tian, CJ Guo, JF Jiang, XQ Shang… - Progress in Modern …, 2010 - cabdirect.org
Objective: To observe the expression and significance of hormothyrin and thyroid hormone
in thyroid cancer. Methods: The expression of hormothyrin (TSH) and thyroid hormone (TT3 …