Augmented 18F-FDG uptake in activated monocytes occurs during the priming process and involves tyrosine kinases and protein kinase C

JY Paik, KH Lee, YS Choe, Y Choi… - Journal of Nuclear …, 2004 - Soc Nuclear Med
Activated monocytes with a high 18F-FDG accumulation can affect the results of clinical PET
studies. To better understand the mechanisms regulating monocytic 18F-FDG uptake, we …

Dissociation between respiratory burst activity and deoxyglucose uptake in human neutrophil granulocytes: implications for interpretation of 18F-FDG PET images

HA Jones, KA Cadwallader, JF White… - Journal of Nuclear …, 2002 - Soc Nuclear Med
Neutrophil granulocytes play a key role in the pathogenesis of a wide variety of pulmonary
diseases. In many such conditions, the injury observed reflects the activation status rather …

Comparison of methods to quantitate 18F-FDG uptake with PET during experimental acute lung injury

DL Chen, MA Mintun, DP Schuster - Journal of Nuclear Medicine, 2004 - Soc Nuclear Med
PET with 18F-FDG may be useful for quantifying neutrophilic activation. We previously
demonstrated that pulmonary neutrophil sequestration could be detected during acute lung …

Characterization of 18F-FDG uptake in human endothelial cells in vitro

S Maschauer, O Prante, M Hoffmann… - Journal of Nuclear …, 2004 - Soc Nuclear Med
The contribution of 18F-FDG uptake by endothelial cells to uptake values measured by PET
in various tissues is as yet unclear. We therefore sought to characterize 18F-FDG uptake in …

Correlations between 18F-FDG uptake by bone marrow and hematological parameters: measurements by PET/CT

Y Murata, K Kubota, M Yukihiro, K Ito… - Nuclear medicine and …, 2006 - Elsevier
The aim of this study was to investigate the correlations between 18F-FDG uptake by bone
marrow and various hematological parameters. Forty-eight patients who underwent FDG …

Increased 18F-FDG uptake in a model of inflammation: concanavalin A-mediated lymphocyte activation

T Ishimori, T Saga, M Mamede… - Journal of Nuclear …, 2002 - Soc Nuclear Med
The aim of this project was to study a mechanism that might explain the increased uptake of
18F-labeled FDG seen in inflammation. The approach chosen was to examine the effect on …

Shortened PET data acquisition protocol for the quantification of 18F-FDG kinetics

LG Strauss, A Dimitrakopoulou-Strauss… - Journal of Nuclear …, 2003 - Soc Nuclear Med
A modified short dynamic protocol was defined and evaluated to predict kinetic parameters
of 18F-FDG metabolism from a dynamic data acquisition. Methods: The evaluation included …

Use of insulin to improve [18F] fluorodeoxyglucose labelling and retention for in vivo positron emission tomography imaging of monocyte trafficking

JY Paik, KH Lee, SS Byun, YS Choe… - Nuclear medicine …, 2002 - journals.lww.com
While 18 F-FDG labelling of monocytes would allow in vivo trafficking with positron emission
tomography (PET), present methods suffer from poor retention of radioactivity. We …

18F-FDG kinetics parameters depend on the mechanism of injury in early experimental acute respiratory distress syndrome

N De Prost, Y Feng, T Wellman, MR Tucci… - Journal of Nuclear …, 2014 - Soc Nuclear Med
PET with 18F-FDG allows for noninvasive assessment of regional lung metabolism reflective
of neutrophilic inflammation. This study aimed at determining during early acute lung injury …

Likely Common Role of Hypoxia in Driving 18F-FDG Uptake in Cancer, Myocardial Ischemia, Inflammation and Infection

Y Yao, YM Li, ZX He, AC Civelek… - Cancer biotherapy & …, 2021 - liebertpub.com
First introduced in 1976, 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography
(PET) has become an indispensable tool for diagnosis and prognostic evaluation of tumors …