Optimizing Strategies for Immune Checkpoint Imaging with Immumo-PET in Preclinical
Study Page 1 1 Optimizing Strategies for Immune Checkpoint Imaging with Immuno-PET in …

Immune checkpoint blockade has emerged as a promising cancer treatment paradigm.
Unfortunately, there are still a large number of patients and malignancies that do not …

Treatment with immune checkpoint inhibitors (ICIs), such as antiprogrammed death-1 (PD-
1), antiprogrammed-death ligand-1 (PD-L1), and anticytotoxic T-lymphocyte antigen-4 …

Despite the remarkable clinical successes of immune checkpoint inhibitors (ICIs) in various
advanced cancers, response is still limited to a subset of patients that generally exhibit …

Antibodies that block immune checkpoints, also called immune checkpoint inhibitors (ICI),
have demonstrated impressive anti-tumor efficacy. The success of ICIs results from a …

Abstract Background Immune checkpoint inhibitors (ICIs) have made significant progress in
oncotherapy improving survival of patients. However, the benefits are limited to only a small …

Immunotherapy with checkpoint inhibitors demonstrates impressive improvements in the
treatment of several types of cancer. Unfortunately, not all patients respond to therapy while …

Advances in immune modulation for cancer and inflammation warrant parallel development
of imaging technologies to gauge in situ immune activity. We have developed a toolbox of …

Abstract Introduction Immunotherapy targeting PD-1/PD-L1 immune checkpoint inhibition
(ICI) is efficacious in various solid and hematologic malignancies. However, the response …

Cancer immunotherapy, especially immune-checkpoint inhibitors (ICIs), has paved a new
way for the treatment of many types of malignancies, particularly advanced-stage cancers …