Signaling pathways that drive 18F-FDG accumulation in cancer
18F-FDG measures glucose consumption and is an integral part of cancer management.
Most cancer types upregulate their glucose consumption, yielding elevated 18F-FDG PET …
Most cancer types upregulate their glucose consumption, yielding elevated 18F-FDG PET …
[HTML][HTML] Revisit 18F-fluorodeoxyglucose oncology positron emission tomography:“systems molecular imaging” of glucose metabolism
B Shen, T Huang, Y Sun, Z Jin, XF Li - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract 18 F-fluorodeoxyglucose (18 F-FDG) positron emission tomography has become an
important tool for detection, staging and management of many types of cancer. Oncology …
important tool for detection, staging and management of many types of cancer. Oncology …
A novel radiotracer to image glycogen metabolism in tumors by positron emission tomography
The high rate of glucose uptake to fuel the bioenergetic and anabolic demands of
proliferating cancer cells is well recognized and is exploited with 18F-2-fluoro-2-deoxy-d …
proliferating cancer cells is well recognized and is exploited with 18F-2-fluoro-2-deoxy-d …
Oncogene pathway activation in mammary tumors dictates FDG-PET uptake
JV Alvarez, GK Belka, TC Pan, CC Chen… - Cancer research, 2014 - AACR
Increased glucose utilization is a hallmark of human cancer that is used to image tumors
clinically. In this widely used application, glucose uptake by tumors is monitored by positron …
clinically. In this widely used application, glucose uptake by tumors is monitored by positron …
Imaging cancer metabolism: underlying biology and emerging strategies
AR Pantel, D Ackerman, SC Lee… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Dysregulated cellular metabolism is a characteristic feature of malignancy that has been
exploited for both imaging and targeted therapy. With regard to imaging, deranged glucose …
exploited for both imaging and targeted therapy. With regard to imaging, deranged glucose …
18F-Fluorodeoxy-glucose Positron Emission Tomography Marks MYC-Overexpressing Human Basal-Like Breast Cancers
N Palaskas, SM Larson, N Schultz, E Komisopoulou… - Cancer research, 2011 - AACR
In contrast to normal cells, cancer cells avidly take up glucose and metabolize it to lactate
even when oxygen is abundant, a phenomenon referred to as the Warburg effect. This …
even when oxygen is abundant, a phenomenon referred to as the Warburg effect. This …
[HTML][HTML] Involvement of cancer-derived EMT cells in the accumulation of 18F-fluorodeoxyglucose in the hypoxic cancer microenvironment
S Sugita, M Yamato, T Hatabu, Y Kataoka - Scientific reports, 2021 - nature.com
A high rate of glycolysis, one of the most common features of cancer, is used in positron
emission tomography (PET) imaging to visualize tumor tissues using 18F …
emission tomography (PET) imaging to visualize tumor tissues using 18F …
[HTML][HTML] Mechanisms underlying 18F-fluorodeoxyglucose accumulation in colorectal cancer
K Kawada, M Iwamoto, Y Sakai - World journal of radiology, 2016 - ncbi.nlm.nih.gov
Positron emission tomography (PET) with 18 F-fluorodeoxyglucose (FDG) is a diagnostic
tool to evaluate metabolic activity by measuring accumulation of FDG, an analogue of …
tool to evaluate metabolic activity by measuring accumulation of FDG, an analogue of …
Does 2-FDG PET accurately reflect quantitative in vivo glucose utilization?
JR Barrio, SC Huang, N Satyamurthy… - Journal of Nuclear …, 2020 - Soc Nuclear Med
2-Deoxy-2-18F-fluoro-d-glucose (2-FDG) with PET is undeniably useful in the clinic, being
able, among other uses, to monitor change over time using the 2-FDG SUV metric. This …
able, among other uses, to monitor change over time using the 2-FDG SUV metric. This …
[HTML][HTML] 18F-fluoro-2-deoxy-d-glucose (FDG) uptake. What are we looking at?
In the last decade, the possibility to map glucose consumption with 2-[18F] fluoro-2-deoxy-D-
glucose (FDG) imaging profoundly modified the daily activity of most nuclear medicine …
glucose (FDG) imaging profoundly modified the daily activity of most nuclear medicine …