Preclinical evaluation of 18F-PSMA-1007, a new prostate-specific membrane antigen ligand for prostate cancer imaging

J Cardinale, M Schäfer, M Benešová… - Journal of Nuclear …, 2017 - Soc Nuclear Med
In recent years, several radiotracers targeting the prostate-specific membrane antigen
(PSMA) have been introduced. Some of them have had a high clinical impact on the …

[HTML][HTML] 44Sc-PSMA-617 for radiotheragnostics in tandem with 177Lu-PSMA-617—preclinical investigations in comparison with 68Ga-PSMA-11 and 68Ga-PSMA …

CA Umbricht, M Benešová, RM Schmid, A Türler… - EJNMMI research, 2017 - Springer
Background The targeting of the prostate-specific membrane antigen (PSMA) is of particular
interest for radiotheragnostic purposes of prostate cancer. Radiolabeled PSMA-617, a 1, 4 …

Preclinical evaluation and pilot clinical study of Al18F-PSMA-BCH for prostate cancer PET imaging

T Liu, C Liu, X Xu, F Liu, X Guo, N Li… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA)–targeted radioligands have played an
important role in the diagnosis of prostate cancer. In this study, we developed an Al18F …

[HTML][HTML] Recent advancements in 18F-labeled PSMA targeting PET radiopharmaceuticals

S Piron, J Verhoeven, C Vanhove, F De Vos - Nuclear Medicine and …, 2022 - Elsevier
Prostate specific membrane antigen (PSMA) is an attractive target for molecular imaging of
prostate cancer and several other solid tumors because of its overexpression in prostate …

[HTML][HTML] F-18 labelled PSMA-1007: biodistribution, radiation dosimetry and histopathological validation of tumor lesions in prostate cancer patients

FL Giesel, B Hadaschik, J Cardinale, J Radtke… - European journal of …, 2017 - Springer
Purpose The prostate-specific membrane antigen (PSMA) targeted positron-emitting-
tomography (PET) tracer 68 Ga-PSMA-11 shows great promise in the detection of prostate …

18F-Labelled PSMA-1007 shows similarity in structure, biodistribution and tumour uptake to the theragnostic compound PSMA-617

FL Giesel, J Cardinale, M Schäfer, O Neels… - European journal of …, 2016 - Springer
The biochemical and radiological responses to radionuclide therapy with 177Lu-PSMA-617
targeting prostate-specific membrane antigen (PSMA) make it a promising approach to the …

The theranostic PSMA ligand PSMA-617 in the diagnosis of prostate cancer by PET/CT: biodistribution in humans, radiation dosimetry, and first evaluation of tumor …

A Afshar-Oromieh, H Hetzheim… - Journal of Nuclear …, 2015 - Soc Nuclear Med
PET imaging with the prostate-specific membrane antigen (PSMA)–targeted radioligand
68Ga-PSMA-11 is regarded as a significant step forward in the diagnosis of prostate cancer …

[HTML][HTML] Preclinical investigations and first-in-human application of 152Tb-PSMA-617 for PET/CT imaging of prostate cancer

C Müller, A Singh, CA Umbricht, HR Kulkarni… - EJNMMI research, 2019 - Springer
Background For almost a decade, terbium radioisotopes have been explored for their
potential theragnostic application in nuclear medicine: 152 Tb and 155 Tb are the …

The rise of PSMA ligands for diagnosis and therapy of prostate cancer

A Afshar-Oromieh, JW Babich… - Journal of Nuclear …, 2016 - Soc Nuclear Med
The prostate-specific membrane antigen (PSMA) has received increased consideration
during the past few years as an excellent target for both imaging and therapy of prostate …

PET imaging of prostate cancer xenografts with a highly specific antibody against the prostate-specific membrane antigen

U Elsässer-Beile, G Reischl, S Wiehr… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA), a transmembrane glycoprotein, is highly
expressed by virtually all prostate cancers and is currently the focus of several diagnostic …