Bone marrow is usually dose-limiting for radioimmunotherapy. In this study, we directly
estimated red marrow activity concentration and the self-dose component of absorbed …

Radioimmunotherapy has been under way as a major field of research in nuclear medicine
for nearly 20 y. However, advances have been slow, and only now can we expect the first …

PET/CT imaging allows for image-based estimates of organ and red marrow (RM) residence
times. The aim of this study was to derive PET/CT-based radiation dosimetry for 89Zr …

For calculation of radiation dose to the marrow, standard dosimetry for radiopharmaceuticals
that do not bind to the marrow includes dose contributions from radioactivity in blood and the …

Red marrow is usually the dose-limiting organ during radioimmunotherapy. Several non-
invasive approaches to calculate the red marrow dose have been proposed. We compared …

Immuno-PET as a scouting procedure before radioimmunotherapy (RIT) aims at confirming
tumor targeting and accurately estimating radiation dose delivery to both tumor and normal …

Radioimmunodetection of tumours with monoclonal antibodies is becoming an established
procedure. Positron emission tomography (PET) shows better resolution than normal …

Myelotoxiclty is the dose-limiting factor in radioimmunotherapy. Traditional methods most
commonly used to estimate the radiation adsorbed dose to the bone marrow of patients …

BACKGROUND The method for red marrow dosimetry in radioimmunotherapy, in the
absence of specific activity uptake in red marrow, is based on the activity measured in the …

@ S (RM@ — h) X m@/mRB, E4@. 2 where h is other organ sources excluding RM, mm is
the mass of the total body (TB) and S (RM@ — TB) is the S value from TB to RM. For …