SCHEME1. Structuresofprogesteroneandsyntheticprog…. adrenalectomized adult male rats
(â€-. 1nM type II sites) with [3H] RU28362 as the tracer while the mineralocorticoid receptor …

We have prepared and evaluated three metal conjugates of a progestin-monoamine-
monoamide (MAMA') bisthiol chelate system. These conjugates of rheniumand technetium …

In order to investigate the possibility of developing diagnostic imaging agents for steroid-
positive tumors that are labeled with the readily available radionuclide technetium-99m, we …

Specific, estrogen-inducible, nuclear radioactivity uptake has been demonstrated in the
uterus, pituitary and hypothalamus of immature female rats after injection of a highly potent …

Abstract Localization of [3 H] R-5020, a potent synthetic progestin, was examined by
radioautography in the central nervous system and the genital tract of estrogen-primed …

MATERIALS AND METHODS The preparation of the (tri-n-butylstannyl) vinyl precursors from
estrone-3-methyl ether and RU-26605 with trans-1, 2-bis (tri-n-butylstannyl) ethylene(22) …

Despite nearly two decades of research since the presence of steroid receptors was first
demon strated, investigators have only recently recorded substantial progress in receptor …

MATERIALS AND METHODS Tetrahydrofuran (THF) wasdistilled from sodium benzophe
none ketyl and stored over molecular sieves (0.4 nm). Lithium aluminum hydride was …

A double isotope dilution method is described for the quantitative determination of
progestins in rat ovarian vein blood. Pure samples and extracts from blood (which include …

To develop androgen and progesterone receptor-based radioligands for SPECT imaging we
synthesized several radioiodinated 17α-iodovinyl testosterone and 19-nortestosterone …