M. this issue of the Journal calls at tention to apersistent challenge facing nuclear medicine:
the quest for a reli able imaging agent to detect active and mature thrombi that will contribute …

Development of a method to selectively label platelets in whole blood in vitro or in vivo is a
highly desirable goal. The authors have investigated the labeling with I-123, I-131, and In …

Platelets (P) labeled with low concentrations of an I-123 or In-111 labeled anti-P monoclonal
antibody (7E3) were shown earlier to successfully image in-vivo thrombi. This study was …

Labeling platelets with monoclonal antibodies in whole blood for imaging thrombi is less
cumbersome than the established 111 In-oxine method. 7E3, a murine monoclonal antibody …

Most of the components of the thrombotic and fibrinolytic systems have at some time been
evaluated as a means of carrying a radiolabel specifically to thrombi, although very few have …

Thrombus detection and localization is of cardinal importance in clinical medicine. The
currently available method using autologous 111In-labeled platelets is too lengthy and …

Detection of thrombi in the extremities and in the trunk, including coronary and carotid
thrombi, is extremely important. of equal importance is the ability to visualize the interaction …

20. JungM, KietterK, DudczakR, et aLDeepvein thrombos@: schi@ cd@ with In-ill
labeledmonoclonalantifibrinantibodies. Radi ology 1989, 173: 469— 475. 21. Walker K …

In canine experimental models of femoral arterial and venous thrombosis, the feasibility of
thrombus imaging with 99Tcm-labelled monoclonal antibody SZ-51 to an [alpha]-granule …

A new era, the “thrombolytic era,” has recently been hailed [1]. This enthusiastic
proclamation is based mainly on the impressive achievements of thrombolytic therapy in …