[PDF][PDF] Scintigraphic portrayal of beta receptors in the heart

JC Sisson, DM Wieland, RA Koeppe… - Journal of Nuclear …, 1991 - Soc Nuclear Med
Injections of test agents were made over a few seconds into an exposedfemoralveinunderanesthesiainduc…
chloral hydrate. For all but the saturation kinetics experiment, †2'I-ICYPas either the (—) …

[PDF][PDF] Metabolism of iodine-123-BMIPP in perfused rat hearts

Y Yamamichi, H Kusuoka, K Morishita… - Journal of Nuclear …, 1995 - Soc Nuclear Med
MATERIALS AND METHODS MaleSprague-Dawleyrats (240— 300g bodyweight)
wereanes thetized with thiopentalsodium (38mg/kgi. p., Tanabe Se@ akU, Osaka, Japan) …

The use of tritium labeled compounds to develop gamma-emitting receptor-binding radiotracers

B Francis, WC Eckelman, MP Grissom… - International journal of …, 1982 - Elsevier
In an effort to evaluate receptor binding drugs for their potential as gamma labeled
radiopharmaceuticals suitable for clinical heart scanning, in vivo data were compared with …

In vivo receptor binding of iodinated beta-adrenoceptor blockers.

WC Eckelman, RE Gibson, F Vieras… - Journal of Nuclear …, 1980 - europepmc.org
Six radiolabeled beta-adrenoceptor blocking agents with a range of affinity constants were
evaluated as radioindicators for adrenoceptors in guinea-pig heart and lung. All …

Influence of specific activity on myocardial uptake of 123I-MIBG in rats

BH MOCK, MM TULI - Nuclear Medicine Communications, 1988 - journals.lww.com
Heart and lung uptake of 123 I-mIBG was studied in rats lh after injection as a function of
specific activity (mCi mg− 1) and the total loading dose (μg kg− 1) of labelled compound …

The effect of X irradiation on cardiac β-adrenergic receptors in the rabbit

R Timmermans, GB Gerber - Radiation research, 1984 - meridian.allenpress.com
Cardiac β receptors in rabbits were studied at different times following lethal (5 Gy) or
supralethal (10 Gy) whole-body X irradiation. Using the radioactive ligand, it was found that …

[PDF][PDF] High myocardial accumulation of radioiodinated digoxin derivative: a possible Na, K-ATPase imaging agent

Y Fujibayashi, Y Takemura, K Matsumoto… - Journal of Nuclear …, 1992 - Soc Nuclear Med
MATERIALSAND METHODS Iodine-125-digoxin-iodohistamine (bis (O-carboxymethylox
ime)), †251-digoxigenin-iodohistamine (3-oxime), and †251-digoxi genin-iodohistamine …

Effect of exercise-induced activation of sympathetic nerve activity on clearance of123I-MIBG from the myocardium

H Sugihara, K Shiga, K Terada, N Kinoshita… - Annals of nuclear …, 1998 - Springer
The effect of exercise on the cardiac kinetics of 123 I-MIBG was investigated in the present
study. 123 I-MIBG was administered intravenously at rest in 6 healthy male volunteers, and …

Development of radioligands for the imaging of cardiac β-adrenoceptors using SPECT. Part II: Pharmacological characterization in vitro and in vivo of new 123I …

EA Dubois, GA Somsen, JC van den Bos… - Nuclear medicine and …, 1997 - Elsevier
Cardiac β-adrenoceptors are assumed to play a key role in chronic heart failure. Although
several radioligands labeled with 11C or 18F have been synthesized for imaging purposes …

[PDF][PDF] Characterization of beta-adrenoreceptors in vivo with iodine-131 pindolol and gamma scintigraphy

B Hughes, DR Marshall, BE Sobel… - Journal of nuclear …, 1986 - Soc Nuclear Med
The aim of this study to was to assess the feasibility of using iodopindolol to delineate
myocardial beta-adrenoreceptors in vivo. Preliminary biodistribution studies indicated that …