We sought to ascertain the rates and mechanisms of uptake of markers for regional
myocardial blood flows. Methods The rates of exchange of potassium and thallium across …

From venous tracer-dilution curves recorded after 36 pulse injections of 42KCl and 131I-
labeled albumin into the coronary artery inflow of 15 isolated canine heart preparations, we …

Although myocardial scintigraphy with 201thallium is widely applied in humans, the
behavior of thallium at the cellular level is still under discussion. We compared the …

Myocardial extraction of Tl has been postulated to depend on the rate of delivery (flow rate)
and the metabolic state of tissue (ATPase activity). Experiments were performed to assess …

The quantitative relationship between fractional myocardial thallium uptake and radioactive
microsphere-determinedflow was studied in 33 open chest dogs under baseline conditions …

Perfusates were equilibrated with 5% CO2-95% air or 5% CO2-95% nitrogen for normoxia
and hypoxia, respectively. Washout thallium kinetics were then observed during perfusion …

METHODS All experiments utilized an isolated isovolumetrically con tracting rabbit heart as
previously described in detail (11). The coronary perfusion rate was controlled by a constant …

MATERIALS AND METHODS Experiments were performed using 42Kand 131Cs. When
both radionuclides were to be compared, they were mixed and administered as a single …

The specific effect of hyperaemia on thallium redistribution is not known. Therefore, we
evaluated the effect of initial (group A) and delayed (group B) hyperaemia on thallium …

The pathophysiological correlates of thallium-201 (201T1) myocardial uptake were studied
in a 24-hour-old closed-chest canine infarct model. Reduction in regional 201T1 uptake …