The identificationof model parametersnecessitated knowledge of the plasma time-
concentration curve C (t) which was used as the inputfunction in subsequent modeling. To …

The in vivo quantification of myocardial muscarinic receptors has been obtained in six
closed-chest dogs by using positron emission tomography. The dogs were injected with a …

The feasability of PET determination of myocardial muscarinic acetylcholine receptor
(mAChR) density has been demonstrated in dogs and humans. The results of the PET …

The feasibility of studying myocardium muscarinic receptors, non invasively, in a “live” being
can be demonstrated using positron emission tomography (PET) and a ligand labelled by …

[en] It has been recently demonstrated that it was possible to characterize in vivo
myocardium muscarinic receptors by injecting baboons with the antagonist …

The muscarinic receptor was studied in vivo in the human heart by a noninvasive method,
positron emission tomography (PET). The study showed that the binding sites of 11C …

Abstract Positron Emission Tomography (PET) was used to analyse in vivo antagonist
binding to human myocardial muscarinic cholinergic receptor. The methiodide salt of the …

DISCUSSION (R)-[― C}-VC-002 meets all the criteria necessary for the determination of
muscarinic receptor densities in human lungs by means of a multiple injection protocol. The …

A method for labeling MQNB (Methiodide quinuclidinyl benzilate) with carbon-11 using 11 C-
methyl iodide is reported. Injectable labeled product (100 mCi; max. 200 mCi) …

BACKGROUND Decreased myocardial adenylate cyclase activity in response to guanine
nucleotide stimulation has been recently demonstrated in denervated myocardium of …