A new cationic complex,[99mTc (tetrofosmin) 2O2]+, where tetrofosmin is the ether
functionalized diphosphine ligand 1, 2-bis [bis (2-ethoxyethyl) phosphino] ethane, has been …

MATERIALS AND METHODS General Unless otherwise specified, all materials were of
reagent grade. Solventsused in high performanceliquid chromatog raphy (HPLC) were …

The favorable nuclear properties in combination with the rich coordination chemistry make
technetium-99m the radioisotope of choice for the development of myocardial perfusion …

Technetium-99m tetrofosmin is a new myocardial perfusion imaging agent that accumulates
rapidly and shows slow clearance from the myocardium. Dynamic acquisition and SPECT …

Background Our objective was to compare the sensitivity and specificity of tetrofosmin, a
new 99mTc-labeled myocardial perfusion imaging agent for the detection of myocardial …

RESULTS All 20 patients in the study group had good quality im ages suitable for clinical
interpretation, as well as for anal ysis of kinetics. Specifically, there was no interpretative …

Pharmaceuticals R&D, Amersham Internationalpic, Amersham, Buckinghamshire, UK;
Department ofNuclear Medicine, Aberdeen Royal Infirmary, Forester/till, Aberdeen, UK; and …

Abstract Technetium-99m (To-99m) tetrofosmin, a new myocardial perfusion imaging agent,
was evaluated at exercise and rest in 50 patients with documented coronary artery disease …

Subjects and Patients with Coronary Artery Disease Page 1 Myocardial Technetium-99m-Tetrofosmin
and Technetium-99m-Sestamibi Kinetics in Normal Subjects and Patients with Coronary Artery …

In recent years, several technetium 99m-labeled myocardial perfusion agents have been
under investigation to determine their utility in assessing regional myocardial blood flow and …