Tumor texture analysis in PET: where do we stand?

I Buvat, F Orlhac, M Soussan - Journal of Nuclear Medicine, 2015 - Soc Nuclear Med
The coexistence of different tumor cells that show distinct morphologic and phenotypic
features either within a tumor or between tumors defines tumor heterogeneity. The …

The promise and limits of PET texture analysis

NM Cheng, YHD Fang, TC Yen - Annals of nuclear medicine, 2013 - Springer
Metabolic heterogeneity is a recognized characteristic of malignant tumors. Positron
emission tomography (PET) texture analysis evaluated intratumoral heterogeneity in the …

Quantifying tumour heterogeneity in 18F-FDG PET/CT imaging by texture analysis

S Chicklore, V Goh, M Siddique, A Roy… - European journal of …, 2013 - Springer
Abstract 18 F-Fluorodeoxyglucose positron emission tomography/computed tomography (18
F-FDG PET/CT) is now routinely used in oncological imaging for diagnosis and staging and …

On some misconceptions about tumor heterogeneity quantification

FJ Brooks - European journal of nuclear medicine and molecular …, 2013 - Springer
Dear Sir, The term “tumor heterogeneity” traditionally refers to whole tumors comprising
distinct cellular subpopulations [1]. More recently, the term connotes the possibility that …

Understanding changes in tumor texture indices in PET: a comparison between visual assessment and index values in simulated and patient data

F Orlhac, C Nioche, M Soussan… - Journal of Nuclear …, 2017 - Soc Nuclear Med
The use of texture indices to characterize tumor heterogeneity from PET images is being
increasingly investigated in retrospective studies, yet the interpretation of PET-derived …

Multiscale texture analysis: from 18F-FDG PET images to histologic images

F Orlhac, B Thézé, M Soussan… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Characterizing tumor heterogeneity using texture indices derived from PET images has
shown promise in predicting treatment response and patient survival in some types of …

Tumor texture analysis in 18F-FDG PET: relationships between texture parameters, histogram indices, standardized uptake values, metabolic volumes, and total …

F Orlhac, M Soussan, JA Maisonobe… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Texture indices are of growing interest for tumor characterization in 18F-FDG PET. Yet, on
the basis of results published in the literature so far, it is unclear which indices should be …

[HTML][HTML] The effect of SUV discretization in quantitative FDG-PET Radiomics: the need for standardized methodology in tumor texture analysis

RTH Leijenaar, G Nalbantov, S Carvalho… - Scientific reports, 2015 - nature.com
FDG-PET-derived textural features describing intra-tumor heterogeneity are increasingly
investigated as imaging biomarkers. As part of the process of quantifying heterogeneity …

Quantitative radiomics: validating image textural features for oncological PET in lung cancer

F Yang, LA Young, PB Johnson - Radiotherapy and Oncology, 2018 - Elsevier
Background and purpose Radiomics textural features derived from PET imaging are of
broad and current interest due to recent evidence of their prognostic value during cancer …

Cancer heterogeneity and imaging

JPB O'Connor - Seminars in cell & developmental biology, 2017 - Elsevier
There is interest in identifying and quantifying tumor heterogeneity at the genomic, tissue
pathology and clinical imaging scales, as this may help better understand tumor biology and …