[PDF][PDF] Cardiac sympathetic denervation from the early stage of Parkinson's disease: clinical and experimental studies with radiolabeled MIBG

H Takatsu, H Nishida, H Matsuo… - Journal of Nuclear …, 2000 - Soc Nuclear Med
Patient Series. Thirty-two parkinsonian patients (15 women, 17 men; mean age [±SD], 67
±7.4 y) were studied. All patients with Parkinson's disease who were admitted to or …

Progressive loss of cardiac sympathetic innervation in Parkinson's disease

ST Li, R Dendi, C Holmes, DS Goldstein - Annals of neurology, 2002 - Wiley Online Library
This study addressed whether cardiac sympathetic denervation progresses over time in
Parkinson's disease. In 9 patients without orthostatic hypotension, 6‐[18F] fluorodopamine …

Cardiac parasympathetic dysfunction concurrent with cardiac sympathetic denervation in Parkinson's disease

M Shibata, Y Morita, T Shimizu, K Takahashi… - Journal of the …, 2009 - Elsevier
We aimed to characterize the relationship between cardiac sympathetic and
parasympathetic dysfunction employing cardiac 123I-meta-iodobenzylguanidine (MIBG) …

Profound cardiac sympathetic denervation occurs in Parkinson disease

T Amino, S Orimo, Y Itoh, A Takahashi… - Brain …, 2005 - Wiley Online Library
In the last few years, cardiac sympathetic dysfunction in Parkinson disease (PD) has been
postulated on the basis of decreased cardiac uptake of sympathoneural imaging tracers …

[PDF][PDF] Loss of 123I-MIBG uptake by the heart in Parkinson's disease: assessment of cardiac sympathetic denervation and diagnostic value

A Satoh, T Serita, M Seto, I Tomita… - Journal of Nuclear …, 1999 - Soc Nuclear Med
Methods: We studied35 patientswith Parkinson'sdisease and 24 control subjects with other
central nervous system diseases. The latter group consisted of 12 subjects with other …

Cardiac sympathetic denervation in Parkinson disease

DS Goldstein, C Holmes, ST Li, S Bruce… - Annals of internal …, 2000 - acpjournals.org
Background: In Parkinson disease, orthostatic hypotension can result from L-dopa treatment
or from sympathetic neurocirculatory failure. The latter is detected by abnormal blood …

Cardiac sympathetic denervation correlates with clinical and pathologic stages of Parkinson's disease

H Fujishiro, R Frigerio, M Burnett… - … : official journal of the …, 2008 - Wiley Online Library
Attention has been drawn to cardiac sympathetic denervation in Parkinson's disease (PD)
based on clinical studies using [123I] metaiodobenzylguanidine scintigraphy; however, the …

Cardiac and extracardiac sympathetic denervation in Parkinson's disease with orthostatic hypotension and in pure autonomic failure

DN Tipre, DS Goldstein - Journal of Nuclear Medicine, 2005 - Soc Nuclear Med
The uptake of 6-18F-fluorodopamine by cardiac noradrenergic nerves enables visualization
of the sympathetic innervation of the left ventricular myocardium by PET. Patients with …

Peripheral sympathetic dysfunction in patients with Parkinson's disease without autonomic failure is heart selective and disease specific

J Taki, K Nakajima, EH Hwang, I Matsunari… - European journal of …, 2000 - Springer
The study was undertaken to investigate by means of iodine-123-labelled
metaiodobenzylguanidine (MIBG) scintigraphy the peripheral sympathetic function in …

Cardiac denervation occurs independent of orthostatic hypotension and impaired heart rate variability in Parkinson's disease

CA Haensch, H Lerch, J Jörg, S Isenmann - Parkinsonism & related …, 2009 - Elsevier
Patients with idiopathic Parkinson's disease (PD) have impaired sympathetically mediated
neurocirculatory innervation. Here we analyzed the correlation between cardiac 123I …