[PDF][PDF] Localization of technetium-99m-glucarate in zones of acute cerebral injury

H Yaoita, T Uehara, AL Brownell… - Journal of Nuclear …, 1991 - Soc Nuclear Med
METHODS Cell Cufture and Flux Measurements LLC-PK cells, a cell line with multiple
characteristicsof renal proximal tubular cells, were cultured on collagen-coated Nucleopore …

Stable kit formulation of technetium-99m glucarate

JR Ballinger, A Proulx, TD Ruddy - … . Part A. Applied radiation and isotopes, 1991 - Elsevier
Preliminary reports suggest that technetium-99m glucarate (GLC) may be useful for
detection of acute cerebral and myocardial injury and metabolically active tumours. We have …

Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour models

JR Ballinger, V Hsue, AM Rauth - Nuclear medicine …, 2003 - journals.lww.com
Abstract 99m Tc-glucarate is an investigational radiopharmaceutical which has been shown
to accumulate in acute cerebral and myocardial injuries and in some tumours. In the present …

Early scintigraphic detection of experimental myocardial infarction in dogs with technetium-99m-glucaric acid.

C Orlandi, PD Crane, DS Edwards… - Journal of nuclear …, 1991 - europepmc.org
Recent data have generated some interest in technetium-99m-(99mTc) glucaric acid as an
in vivo viability marker. We studied 99mTc-glucaric acid retention in canine models of …

[PDF][PDF] Effect of hypoxia on the accumulation of technetium-99m-glucarate and technetium-99m-gluconate by Chinese hamster ovary cells in vitro

JR Ballinger, DSM Cowan, I Boxen… - Journal of Nuclear …, 1993 - Soc Nuclear Med
METHODS Labeled Compounds Technetium-99m-glucarate,@ mTc@ gluconateand@
mTc@ DTPA were prepared from in-house kits which contained 50@ mol ligand, 3 …

Formulation of lyophilized cold kit for instant preparation of 99mTc-glucarate and its scintigraphic evaluation in experimental models of infarction

AK Babbar, RK Sharma - Indian journal of pharmacology, 2003 - journals.lww.com
Objective: To standardise the optimum labelling conditions for tagging glucaric acid,
formulate a stable cold kit and evaluate it in experimental models of infarction. Methods: A …

[PDF][PDF] Comparison of technetium-99m-glucarate and thallium-201 for the identification of acute myocardial infarction in rats

H Ohtani, RJ Callahan, BA Khaw… - Journal of Nuclear …, 1992 - Soc Nuclear Med
201 (300— 500MCi) was administeredintravenouslyand anterior myocardial images were
recorded 10 mm later with the camera peaked at the 80 keV x-ray with a 20% window. At the …

[PDF][PDF] Filling out phenomenon with technetium-99m HM-PAO brain SPECT at the site of mild cerebral ischemia

K Hayashida, T Nishimura, S Imakita… - Journal of nuclear …, 1989 - Soc Nuclear Med
at the Site of Mild CerebralIschemia Page 1 ipophilic chelate of technetium-99m (@mTc)with
d,l isomer of hexamethylpropyleneamine oxime (HM PAO(1) can crossthe blood-brainbarrierwith …

[PDF][PDF] Distribution of deoxyglucose and technetium-99m-glucarate in the acutely ischemic myocardium

H Yaoita, AJ Fischman, R Wilkinson… - Journal of Nuclear …, 1993 - Soc Nuclear Med
MATERIALSAND METHODS AnImal Model Myocardial ischemia and reperfusion injury was
induced in 5 (fasting) and17 (fed) NewZealandwhiterabbitsweighingabout3 kg. Under …

Early detection of infarct in reperfused canine myocardium using 99mTc-glucarate

DR Okada, G Johnson, Z Liu… - Journal of nuclear …, 2004 - Soc Nuclear Med
99mTc-Glucarate is an infarct-avid imaging agent with the potential for very early detection
of myocardial infarction. The purposes of this study using a canine model were to determine …