[PDF][PDF] Detection of reperfusion injury using PET in a monkey model of cerebral ischemia
H Takamatsu, H Tsukada, T Kakiuchi… - Journal of Nuclear …, 2000 - Soc Nuclear Med
Several studies of focal ischemia and reperfusion in animal models have proposed that
reperfusion contributes to brain damage. However, the extent to which reperfusion affects …
reperfusion contributes to brain damage. However, the extent to which reperfusion affects …
A metabolic threshold of irreversible ischemia demonstrated by PET in a middle cerebral artery occlusion–reperfusion primate model
P Frykholm, JLR Andersson, J Valtysson… - Acta neurologica …, 2000 - Wiley Online Library
Objective–to evaluate the predictive value of measurements of regional cerebral blood flow
(CBF), oxygen metabolism (CMRO2) and oxygen extraction ratio (OER) for assessment of …
(CBF), oxygen metabolism (CMRO2) and oxygen extraction ratio (OER) for assessment of …
Validation of MRI determination of the penumbra by PET measurements in ischemic stroke
WD Heiss, OZ Weber - Journal of Nuclear Medicine, 2017 - Soc Nuclear Med
The concept of the ischemic penumbra was formulated on the basis of animal experiments
showing functional impairment and electrophysiologic disturbances with decreasing flow to …
showing functional impairment and electrophysiologic disturbances with decreasing flow to …
Dynamic penumbra demonstrated by sequential multitracer PET after middle cerebral artery occlusion in cats
WD Heiss, R Graf, K Wienhard… - Journal of Cerebral …, 1994 - journals.sagepub.com
Experimental models of focal cerebral ischemia have provided important data on early
circulatory and biochemical changes, but typically their correspondence with metabolic and …
circulatory and biochemical changes, but typically their correspondence with metabolic and …
Progressive derangement of periinfarct viable tissue in ischemic stroke
WD Heiss, M Huber, GR Fink… - Journal of Cerebral …, 1992 - journals.sagepub.com
Sixteen patients were studied by multitracer positron emission tomography (PET) within 6–
48 (mean of 23) h of onset of a hemispheric ischemic stroke and again 13–25 (mean of 15.6) …
48 (mean of 23) h of onset of a hemispheric ischemic stroke and again 13–25 (mean of 15.6) …
PET study of changes in local brain hemodynamics and oxygen metabolism after unilateral middle cerebral artery occlusion in baboons
S Pappata, M Fiorelli, T Rommel… - Journal of Cerebral …, 1993 - journals.sagepub.com
Local cerebral hemodynamics and oxygen metabolism were measured by positron emission
tomography (PET) with the oxygen-15 (15O) steady-state method in baboons, immediately …
tomography (PET) with the oxygen-15 (15O) steady-state method in baboons, immediately …
[PDF][PDF] Visualization of damaged brain tissue after ischemic stroke with cobalt-55 positron emission tomography
HML Jansen, J Pruim, AM vd Vliet… - Journal of Nuclear …, 1994 - Soc Nuclear Med
Methods: The potential role of@ Co@ f@ in vivo brain PET imaging was investigatedin four
patients after ischemic stroke. Resufts: PET showed uptake of 55 (@, 2+ in damaged brain …
patients after ischemic stroke. Resufts: PET showed uptake of 55 (@, 2+ in damaged brain …
Potential of Early [18F]-2-Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography for Identifying Hypoperfusion and Predicting Fate of Tissue in a Rat Embolic …
M Walberer, H Backes, MA Rueger, B Neumaier… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—Experimental stroke models are essential to study in vivo
pathophysiological processes of focal cerebral ischemia. In this study, an embolic stroke …
pathophysiological processes of focal cerebral ischemia. In this study, an embolic stroke …
Tissue at risk of infarction rescued by early reperfusion: a positron emission tomography study in systemic recombinant tissue plasminogen activator thrombolysis of …
WD Heiss, M Grond, A Thiel… - Journal of Cerebral …, 1998 - journals.sagepub.com
Thrombolytic therapy of acute ischemic stroke can be successful only as long as there is
penumbral tissue perfused at rates between the thresholds of normal function and …
penumbral tissue perfused at rates between the thresholds of normal function and …
Identifying hypoxic tissue after acute ischemic stroke using PET and 18F-fluoromisonidazole
SJ Read, T Hirano, DF Abbott, JI Sachinidis… - Neurology, 1998 - AAN Enterprises
Objective: To show that PET with 18F-fluoromisonidazole (18F-FMISO) can detect peri-
infarct hypoxic tissue in patients after ischemic stroke. Background: PET with 15O-labeled …
infarct hypoxic tissue in patients after ischemic stroke. Background: PET with 15O-labeled …