Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography

H Toyama, M Ichise, JS Liow, KJ Modell… - Journal of Nuclear …, 2004 - Soc Nuclear Med
The purpose of this study was to evaluate the feasibility of absolute quantification of regional
cerebral glucose utilization (rCMRglc) in mice by use of 18F-FDG and a small animal PET …

Measurement of cerebral glucose metabolic rates in the anesthetized rat by dynamic scanning with 18F-FDG, the ATLAS small animal PET scanner, and arterial blood …

K Shimoji, L Ravasi, K Schmidt… - Journal of Nuclear …, 2004 - Soc Nuclear Med
Rodent models and genetically altered mice have recently become available to study many
human diseases. A sensitive and accurate PET scanner for small animals would be useful to …

Quantification of cerebral glucose metabolic rate in mice using 18F-FDG and small-animal PET

SY Amy, HD Lin, SC Huang, ME Phelps… - Journal of Nuclear …, 2009 - Soc Nuclear Med
The aim of this study was to evaluate various methods for estimating the metabolic rate of
glucose utilization in the mouse brain (cMRglc) using small-animal PET and reliable blood …

Errors Introduced by Tissue Heterogeneity in Estimation of Local Cerebral Glucose Utilization with Current Kinetic Models of the [18F]Fluorodeoxyglucose Method

K Schmidt, G Lucignani, RM Moresco… - Journal of Cerebral …, 1992 - journals.sagepub.com
The effects of tissue heterogeneity on the estimation of regional cerebral glucose utilization
(rCMRglc) in normal humans with [18F] 2-fluoro-2-deoxy-d-glucose ([18F] FDG) and positron …

Operational lumped constant for FDG in normal adult male rats

J Tokugawa, L Ravasi, T Nakayama… - Journal of Nuclear …, 2007 - Soc Nuclear Med
We determined an operational value for the lumped constant to be used in measurements of
the local rate of cerebral glucose use (lCMRglc) with FDG in normal adult male rats …

[PDF][PDF] Fluorine-18-fluorodeoxyglucose PET to determine regional cerebral glucose utilization: a re-examination

KC Schmidt, G Lucignani, L Sokoloff - Journal of Nuclear Medicine, 1996 - Soc Nuclear Med
PET SCANNERS Recent generations of scanners are more efficient and contain multiple-
rings that allow many planes to be scanned simulta neously in much shorter time intervals …

Regional cerebral glucose metabolism in healthy volunteers determined by fluordeoxyglucose positron emission tomography: appearance and variance in the …

V ANÇEVIC IV, A Alavi, E Souder… - Clinical nuclear …, 2000 - journals.lww.com
Purpose In this study, the contribution of the transaxial, coronal, and sagittal planes in
evaluations of regional cerebral glucose metabolism was investigated in healthy volunteers …

Reproducibility of cerebral glucose utilization measured by PET and the [18F]-2-fluoro-2-deoxy-d-glucose method in resting, healthy human subjects

P Maquet, D Dive, E Salmon, R von Frenckel… - European journal of …, 1990 - Springer
The stability of cerebral glucose utilization was examined in nine right-handed, healthy men
(age, 24.88±2.93 years) using positron emission tomography (PET) and the [18 F] …

[PDF][PDF] Measurement of regional cerebral glucose utilization with fluorine-18-FDG and PET in heterogeneous tissues: theoretical considerations and practical …

G Lucignani, KC Schmidt, RM Moresco… - Journal of Nuclear …, 1993 - Soc Nuclear Med
INB-CNR, Department ofNuclear Medicine University ofMilan, Institute H. San Raffaele,
Milan, Italy and Laboratoi'y of Cerebral Metabolism, National Institute ofMental Health …

In vivo quantitation of glucose metabolism in mice using small-animal PET and a microfluidic device

HM Wu, G Sui, CC Lee, ML Prins… - Journal of Nuclear …, 2007 - Soc Nuclear Med
The challenge of sampling blood from small animals has hampered the realization of
quantitative small-animal PET. Difficulties associated with the conventional blood-sampling …