The improvement of existing techniques and the development of new molecular imaging
methods are an exciting and rapidly developing field in clinical care and research of …

Neurodegenerative disorders such as Alzheimer disease are among today's most alarming
health problems in our aging society. The clinical assessment of neurodegenerative …

Dementia is a highly prevalent problem causing considerable disability and mortality and
exacting great costs to individuals, their families, and society. The 4 most common …

The increasing prevalence of dementia worldwide places a high demand on healthcare
providers to perform a diagnostic work-up in relatively early stages of the disease, given that …

Computed tomography (CT) and magnetic resonance imaging (MRI) provide key structural
information on brain pathophysiology. Positron emission tomography (PET) measures …

Background: There is an urgent need for early diagnosis and treatment of dementia to ease
caregiver burden and medical costs associated with the increasing number of affected …

Introduction Rising life-expectancy in the modern society has resulted in a rapidly growing
prevalence of dementia, particularly of Alzheimer's disease (AD). Dementia turns into one of …

Loss of synapses and neurons is the primary feature of neurodegenerative pathology. The
development of novel, diseasemodifying medication requires the ability to identify patients in …

Over the past few decades, several radiotracers have been developed for neuroimaging
applications, especially in PET. Because of their low steric hindrance, PET radionuclides …

The spectrum of neurodegenerative diseases comprises dementias, Parkinsonian
syndromes, Huntington's disease, amyotrophic lateral sclerosis, and prion diseases. As MRI …