1640 Objectives: Accurate quantitation of amyloid-beta (Aß) plaque load using positron
emission tomography (PET) is important for monitoring Aß accumulation in therapeutic trials …

1180 Introduction: Quantitation of amyloid-PET data is critical to monitor amyloid-beta
plaque changes both in longitudinal observational studies and in interventional trials …

Accurate amyloid PET quantification is necessary for monitoring amyloid-β accumulation
and response to therapy. Currently, most of the studies are analyzed using the static SUV …

Background Kinetic modeling of brain amyloid deposition with [18F]‐florbetaben more
accurately quantifies the binding density to amyloid plaques compared to standardized …

Accumulation of amyloid beta (Aβ) is one of the pathological hallmarks of Alzheimer's
disease (AD), which can be visualized using [18F] florbetapir positron emission tomography …

18F-florbetaben is a novel 18F-labeled tracer for PET imaging of β-amyloid deposits in the
human brain. We evaluated the kinetic model–based approaches to the quantification of β …

Accumulation of amyloid beta can be visualized using [18F] florbetapir positron emission
tomography. The aim of this study was to identify the optimal model for quantifying [18F] …

Background Semiquantitative methods such as the standardized uptake value ratio (SUVR)
require normalization of the radiotracer activity to a reference tissue to monitor changes in …

Positron emission tomography (PET) allows for in vivo visualisation and quantification of
amyloid-β (Aβ) plaques, which are known to play a major role in the development of …

Knowledge about spatial and temporal patterns of β-amyloid (Aβ) accumulation is essential
for understanding Alzheimer disease (AD) and for design of antiamyloid drug trials. Here, we …