MATERIALS AND METHODS Paramagnetic tracer. Colloidal manganese sulfide was
prepared by the coprecipitation of equal molar quantities of manganese acetate and sodium …

The potential use of paramagnetic compounds as nuclear magnetic resonance (NMR)
contrast agents was examined in vitro. The T1 relaxation times for serial dilutions of Cu2+ …

Nuclear magnetic resonance imaging relies upon differences in relaxation times for much of
its ability to resolve anatomical structures and to detect changes in tissue. The natural …

Manganese is a powerful paramagnetic material and potential NMR contrast agent. It
drastically affects the NMR properties of solutions and tissues and is less toxic than most …

Solutions of manganese chloride were force-fed to Sprague-Dawley rats. Magnetic
resonance (MR) imaging was performed on (a) syringes containing different concentrations …

Relaxation time differences are the sources of most of the contrast observed in proton NMR
images, not only among normal organs and tissues but between lesions and the adjacent …

Paramagnetic ions could be theoretically used as NMR contrast agents because of their
effect upon Ti. However, the toxicity of these ions prevents their application. By the formation …

Most contrast agents used in NMR imaging studies to date have been paramagnetic.
However, it is also possible to obtain selective contrast with a ferromagnetic agent, and …

To evaluate its potential as a tissue-specific hepatobiliary magnetic resonance (MR) contrast
agent, manganese chloride was orally administered to rats in increasing doses of 100-1,500 …

Some factors affecting the performance of paramagnetic ions as contrast agents for proton
NMR imaging have been studied. It is demonstrated that the relaxation rate of an aqueous …